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Register Today!February 26, 2014

Using Whole-genome Bisulfite Sequencing to Understand Chromatin State Changes in Cancer

Speakers for this Event:
  • Ben Berman, Ph.D., Assistant Professor, Division of Bioinformatics, Department of Preventive
        Medicine, University of Southern California
        Using Whole-genome Bisulfite Sequencing to Understand Chromatin State Changes in Cancer


  • Ramesh Vaidyanathan, Ph.D., Associate Director of Research and Development, Epicentre
       
    Power of EpiGnomeā„¢: Comprehensive Methylation Coverage from Small Amounts of gDNA

  • Transcriptional regulation is accomplished by both focal cis-regulatory elements (promoters, enhancers, and insulators) and the higher order organization of chromosomes (topological domains). While these chromatin states are associated with a number of different epigenetic marks, DNA methylation (5-methylcytosine) is the most practical for studying primary tumors.

    The presenters from University of Southern California and Epicentre (an Illumina company), will present on how whole-genome bisulfite sequencing (WGBS) is being used to profile dozens of primary tumors from The Cancer Genome Atlas (TCGA) project, how methylation can be accurately measured using next-generation sequencing, and a new method that yields comprehensive methylation coverage from small amounts of gDNA.

    Register Today!

    THIS PROGRAM IS INTENDED FOR
    • Epigenetics or Epigenomics researchers
    • DNA Methylation researchers
    • Cancer and other disease biologists
    • Stem cell researchers
    • Sequencing core facilities
    • Next-generation sequencing facilities
    • R&D directors
    • Medical science liaisons
    ABOUT OUR SPEAKERS

    Benjamin Berman, Ph.D., Assistant Professor, Division of Bioinformatics, Department of Preventive Medicine, University of Southern California

    Prof. Berman is an Assistant Professor in the Division of Bioinformatics of the Department of Preventive Medicine at the University of Southern California (USC). His current research focus is on whole-genome epigenomic analysis of cancer, control of gene regulation by non-coding regulatory elements and the role of nuclear organization alterations in cancer. He is also an active member of the USC Epigenome Center and the Norris Comprehensive Cancer Center, both of the University of Southern California.

    Ramesh Vaidyanathan, Ph.D., Associate Director of Research and Development, Epicentre

    Dr. Vaidyanathan is the Associate Director of Research and Development at Epicentre (an Illumina Company) located in Madison, WI. He received his Ph.D. from Indian Institute of Science, and was a Post Doctoral Associate at the Massachusetts Institute of Technology.

    OUR XTALKS PARTNER FOR THIS EVENT

    EpicentreĀ® (an Illumina Company) manufactures innovative products for life science research, contributing to breakthrough studies in genomics, transcriptomics, and epigenetics. Epicentre offers products for variety of applications, including ribosome profiling, RNA sequencing, gene expression analysis, DNA and RNA purification, PCR and RT-PCR, in vitro transcription, and microbial genomics.

    Register Today!

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