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April 29, 2014

Discover Epigenomic Variation with a Flexible Targeted Bisulfite Sequencing Method

Speakers for this Event:
  • Daniel Burgess, PhD, Group Leader – Sequence Capture, Roche NimbleGen
  • Nathan Springer, PhD, Professor, University of Minnesota
  • Epigenetic researchers face a number of challenges in methylation studies related to breadth, depth, throughput and more. Built on Roche NimbleGen’s proprietary probe design and manufacturing technologies, the SeqCap Epi Enrichment System will enable you to overcome these challenges.

    Dr. Burgess and Dr. Springer will discuss how innovative probe design combined with a unique workflow provides a clearer picture of the epigenomic variation in your samples than any other system currently available. See how you can discover differential methylation efficiently, with custom designs over target selection, lower sample input, higher information retention, and the abilities to capture both strands, detect complex or rare methylation events and reduce false positives.

    The presenters will share the rationale behind the development of this flexible targeted bisulfite sequencing tool and how it has been applied in methylation research.


    Principle investigators, laboratory scientists, genome center directors, clinical researchers, cancer/oncology researchers, agricultural genetic researchers, epigenetic researchers.


    Daniel Burgess, PhD, Group Leader – Sequence Capture, Roche NimbleGen

    Dr. Burgess holds a PhD degree from the Department of Human Genetics at the University of Michigan. He was a Postdoctoral Fellow and then an Assistant Professor of Neurology at Baylor College of Medicine in Houston, Texas. Dr. Burgess joined Roche NimbleGen in 2008, where he has been leading efforts in target enrichment technology and product development for high resolution genome analysis.

    Nathan Springer, PhD, Professor, University of Minnesota

    Nathan Springer performed his PhD research on the consequences of aneuploidy in Dr. Ron Phillips group at the University of Minnesota. He was a post-doctoral researcher in Dr. Shawn Kaeppler's group at the University of Wisconsin where he worked on the characterization of chromatin-related genes in maize. He joined the Department of Plant Biology at the University of Minnesota in 2003. He is currently a Professor in the Department of Plant Biology and the Director of the Microbial and Plant Genomics Institute. Nathan's research group studies natural variation in maize with focuses on structural genomic variation, gene expression variation and epigenomic variation.


    Roche NimbleGen is an innovator in the life sciences market focused on research activities and manufacturing target enrichment probe pools for DNA sequencing. Capitalizing on the efficiencies inherent with parallel enrichment, researchers can now design economical, high throughput, and time-saving next-generation sequencing experiments. Next-generation sequencing combined with Sequence Capture probe pools offers researchers a clearer understanding of genomic structure and function in order to understand the impact of genes on biological processes. We are part of the innovations in sequencing solutions for life science research, now and in the future.

    For information about the recorded archive for this event contact Xtalks at (416) 977-6555 ext 371, or email register@xtalks.com

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