Scientist (Assay Development)

PSC Biotech

Posted on: May 13, 2022

Closing: June 12, 2022

Salary: Undisclosed

Position Type: Full Time

Job Description

PSC Biotech is a leading Biotech Consultancy firm founded in 1996, headquartered in Pomona, California, employing a global team of skilled professional and experts that span across strategically located offices in the United States, Europe, Asia, and the Middle East. PSC operates in 52 countries globally and has served thousands of clients to date.

 

We focus on providing quality consulting services to ensure our client’s success. PSC provides cost-effective solutions, while providing exceptional technical capabilities and customer service to our clients for all projects ranging from supplier quality audits to greenfield projects. We understand that the world of life science is evolving rapidly, and we must continue to offer new products and services to meet our customer’s expectations.

We are hiring an Assay Development Scientist. 
  • Develop and qualify assays for the identification, optimization, and characterization of recombinantly produced therapeutics (i.e. release assays)
  • Development/adaptation of assays for comparisons with innovator therapeutics
  • Grow, maintain, and generate (if necessary) target cell lines for use in cell-based assays for determining activity and potency of recombinant drugs including those made from a plant-based expression platform
  • Develop and standardize fluorescent, chemiluminescent, and flow cytometric based assays
  • Operation and maintenance of the in-house biosafety level 2 (BSL-2) facility
  • Acquire and maintain required analytical instrumentation, reagents, and supplies for molecular, protein, and cell-based activity assays
  • Responsible for screening operations (including scheduling), assay performance, and data flow
  • Responsible for assay development, validation, and implementation to support activities essential for drug development and manufacturing
  • Provide technical information and experimental assay design for recombinant product screening
  • Develop efficient operational models involving assay instrumentation, design, and analysis to streamline the workflow
  • Collect and interpret data for biological characterization assays and comparative studies; assist with data preparation for analysis and reporting
  • Help provide required training and maintain current knowledge of industry standards. May direct and oversee experimental design and results of associates and technicians.
  • Collaborate with members of the Early Stage Product Development Groups (Molecular Biology and Process Development), Manufacturing, Quality Control, and Quality Assurance
  • Develop screening protocols for all types of cell-based assays
  • Participate in evaluation of therapeutic technologies
  • Assist in the preparation and presentation of clear technical reports, publications, and oral presentations

 

Requirements

  • Preferred Ph.D. and/or 4 years’ experience in molecular biology techniques and experience in developing biochemical and cellular assays, especially Enzyme-Linked Immunosorbent Assays (ELISA) type assays
  • Experience in a cGMP regulated environment is required
  • Knowledge of laboratory safety protocols
  • Knowledge of plant-transient expression systems
  • Knowledge of standard analytical techniques, including SDS-PAGE, ELISA, and Western blot
  • Knowledge of optical methods
  • Knowledge and experience of screening reagent, and design of novel assays
  • Skill in documentation and attention to detail
  • Skill in computer functions such as word processors, spreadsheets, data visualization, cell sorting, FACS, Biacore and basic internet usage
  • Ability to make decision and recommendations
  • Ability to demonstrate professionalism with personnel and management
  • Collaborative team player
  • Ability to gather, organize, and analyze information skillfully
  • Ability to lead effectively
  • Strong foundation in experimental design and ability to execute complex experiments
  • Knowledge of post-transactional protein modifications including glycobiology
  • Must be able to communicate effectively through oral and written communication 

 

Benefits

  • Generous Medical, Dental, Vision Benefits
  • Health and Wellness Programs
  • Company Paid Short and Long Term Disability and Life Insurance 
  • Bonus Opportunities
  • 401(k) Match
  • Paid Time Off
  • Numerous Holidays
  • Flexible Work Arrangements Based on Role 
  • Gym Membership Reimbursements
  • Continuous Education, Training and Development 
  • Opportunities for Promotions and Growth 
  • Coaching and Mentorship Programs 
#LI-PM1

PSC Biotech

Posted on: May 13, 2022

Closing: June 12, 2022

Salary($): Undisclosed

Position Type: Full Time

Career Focus: Admin, Operations, Quality

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