Vice President, Nucleic Acids Technology Development

Arranta Bio

Posted on: October 13, 2021

Closing: November 12, 2021

Salary: Undisclosed

Position Type: Full Time

Job Description

Arranta Bio is a visionary contract development and manufacturing organization (CDMO) that partners with companies seeking to develop and manufacture complex biological drugs and innovative therapies. Our dedicated team, state-of-the-art facilities, and unparalleled resources are crucial for advancing products from development to commercial launch. Our vision is to be the trusted and innovative CDMO partner for advanced therapy pioneers, so that we can bring life-changing therapeutics to patients.  We partner with our clients to make treatments that can benefit vast patient populations, working across many indications. Arranta Bio’s mission is to change healthcare through our intrepid and daring team engaging with clients to develop, manufacture, and supply breakthrough therapies that transform lives.  Arranta Bio continues to expand capacity and development and manufacturing services across multiple sites with technology platforms designed to meet the evolving demands of our clients and partners.


Arranta hires people who are committed and passionate to the goal of bringing life enhancing products to patients. We want top talent who will render ideas and a relentless desire towards accomplishing our mission; when a job becomes a passion, it makes you feel ALIVE.

Here at Arranta Bio, we embrace ALIVE – our core values that we live and breathe daily! We are Agile, Leading, Innovating, Value Creating, and Engaging.

We embrace our challenges as opportunities.

We are empowered to think and act.

We never settle; we strive to improve through purposeful creativity.

We build aligned teams who learn, grow, and deliver.

We are committed to building strong relationships.

Are you ready to come ALIVE with a daring and intrepid team?  Don’t wait another minute; Apply today!


Arranta is offering the first end-to-end platform for full integration of cGMP manufacturing of critical raw materials, in-vitro transcription, mRNA purification, LNP formulation, and sterile fill/finish.  Building upon existing capabilities in fermentation and plasmid production, Arranta intends to support product innovators using the mRNA platform to develop vaccines, for example, targeting infectious diseases, as well as therapeutic vaccines, such as though targeting cancer.

The individual will work with scientific, operations, and business leaders to design and implement the strategy for nucleic acid development and manufacturing services for Arranta Bio.  This will include the latest developments in mRNA synthesis, formulation, and delivery supporting internal platform development and client programs.  This Senior Leadership position will establish and build the team and capabilities delivering QbD process development, characterization, MSAT, and commercialization services for nucleic acids (e.g. mRNA and LNP) at our newly constructed state-of-the-art facility in Watertown, MA.

The individual should be equipped with a strong technical skillset, proven track record of delivering with a hands-on approach, and the highest degree of focus on Safety, cultivation of talent and a positive work culture.


  • Establish and lead the nucleic acids technical organization including but not limited to platform development, process development, process characterization and commercialization
  • Accountable for all internal and external nucleic acid development programs from proof-of-concept through commercialization
  • Build upon the established plasmid production platform(s) to ensure continuity with existing clients, bolster technical acumen, and increase scope of business offerings
  • Define and lead the execution of a technology strategy for end-to-end nucleic acid development, manufacture, and commercialization
  • Evaluate technology and make strategic recommendations on acquisitions, partnerships, and technology establishment
  • Provide direct, hands-on technical oversight for internal and client programs being the face of all technical communication to client(s)
  • Identify and develop scientific talent and be a champion of continuous improvement
  • Support the commercial function in the assessment of new opportunities and provide appropriate technical and programmatic input to prospective customers



Experience and Skills


  • Ph.D. in biochemical engineering, biological sciences, or relevant field with 10-15 years experience
  • Significant drug and/or platform development experience in clinical/commercial with a track record of management and delivery of multiple programs
  • Experience in the development and manufacture of mRNA and/or oligonucleotides
  • Deep expertise in nucleic acid process development (purification, formulation, and/or LNP, etc.)
  • Entrepreneurial experience dealing with customers in product development.
  • Working knowledge of cGMPs related to the production of microbial therapeutics
  • Ability to work by influencing peers and their reports and gain their cooperation in dealing with multiple priorities in the delivery of projects
  • Strategic leadership and conceptual thinking to ensure that a cost-effective organization is put in place and developed
  • Strong people management and organizational skills; ability to prioritize and manage through complex processes/projects
  • Ability to interpret and manipulate data, define problems, establish facts, draw valid conclusions, and make decisions
  • Ability to deal with abstract and concrete variables in situations where only limited standardization exists
  • Extremely high levels of initiative and tenacity
  • Excellent oral and written communication skills


The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

  • The employee is frequently required to stand; sit; use hands to finger, handle, or feel; reach with hands and arms; and talk or hear.
  • The employee is occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl.
  • The employee must frequently lift and/or move up to 10 pounds and occasionally lift and/or move up to 25 pounds.
  •  Specific vision abilities required by this job include close vision, and ability to adjust focus.
  • In the performance of the duties of this job the employee is required to travel occasionally, drive a motor vehicle.
  • Communicate using telephone and e-mail.


COVID19 Vaccine required to come on site; Individuals seeking an exemption from this requirement for medical or religious reasons should reach out to Human Resources for an accommodation.  


  • Phone reimbursement policy for qualified individuals
  • Free parking
  • Highly competitive healthcare with many plan options:
  • Medical (HMO/PPO/EPO)
    • Dental
    • vision
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • Up to 10 weeks of 100% paid maternity leave
  • 2 weeks of 100% paid paternity, domestic partner, & adoption leave
  • Educational assistance program
  • 401k (traditional and Roth offered) with 100% match on first 5% deferred.
  • A suite of Arranta Bio paid insurance coverage, including life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • Employee Referral program
  • Competitive PTO plan, in addition to 10 company paid holidays (includes 2 floating holidays)

Arranta Bio

Posted on: October 13, 2021

Closing: November 12, 2021

Salary($): Undisclosed

Position Type: Full Time

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