Overview

Primarily responsible for the assay design, execution, and presentation of biophysical characterizations and working collaboratively with a team of experienced scientists to facilitate all aspects of the Biophysics Laboratory.

Responsibilities

• The scientist plays a key role in the biophysics team - responsible for developing and executing biophysical characterizations including but not limited to HT-SPR, MST, DSF based screening and characterizations pertaining to a variety of drug discovery campaigns.
• The scientist will also work closely with a diverse team of scientists to facilitate various aspects of discovery biology assays (HTS laboratory).
• Ability to run assays based on established protocols.
• Develops new methods or assays based on minimal information or protocols.
• Ability to learn the use of acoustic liquid handlers, semi-automated liquid dispensers, plate readers, and other lab instruments.
• Maintains ELN in a well-organized manner. All necessary information is recorded for client facing purposes.
• Complies with all safety rules, practices good housekeeping, and maintains safe workplace without supervision.
• Regularly reviews goals and objectives with supervisor.
• Assumes responsibility for technical accuracy of work.
• Self- Motivated, requires minimal supervision and determines next steps with minimal guidance
• Makes logical suggestions of likely causes of problems and independently suggests solutions.
• Makes decisions based on an understanding of client program goals.
• Communicates frequently with client and provide frequent update reports.
• Contributes and/or participates in promotional activities (conferences, publications, poster presentations, lunch and tours, etc.)

Qualifications

Experience / Education

• PhD + 1 or MS + 5 or BS + 8 years of industry experience in biophysical assays and biological sciences.

Knowledge / Skills / Abilities:

• Experience with biophysical characterization of small molecules and biologics interactions using Surface Plasmon Resonance (SPR).
• Experience with other biophysical techniques such as Differential Scanning Fluorimetry (nanoDSF/DSF/TSA), Dynamic Light Scattering (DLS), MicroScale Thermophoresis (MST/SpS), Bio-Layer Interferometry (BLI), Circular Dichroism (CD) and/or Isothermal Titration calorimetry (ITC) is a plus.
• The candidate must have a strong understanding of antibody-antigen biomolecular interactions, kinetics, and thermodynamics, and various aspects of immunology.
• Hand-on experience with handling and executing experiments on Carterra LSA, Biacore SPR, NanoTemper Panta, NanoTemper Dianthus, Malvern/TA ITC, and familiarity with antibody production & purification workflows are a plus.
• Demonstrates attention to details and concern for impact
• Records experimental procedures and results in notebook
• Presents data clearly and concisely
• Ability to search scientific literature and suggest protocols and methods
• Ability to think critically and scientifically
• Demonstrates competence in relevant technical aspects of scientific discipline which allows for increasing level of independence
• Able to work in a fast paced environment
• Must work well with others in a team environment
• Effectively communicates with others by giving and receiving feedback
• Participates actively in meetings
• Well organized, detail oriented, and adaptable to changes
• Excellent oral and written communication skills
• Excellent interpersonal skills
• Computer skills: knowledge of internet research, MS Word, Excel, Outlook, and PowerPoint. Ability to learn instrument and data analysis software
• Good time management and multi-tasking skills in order to complete multiple projects within timelines.
• Expert knowledge of commonly used concepts, practices, and procedures within biological R&D laboratory setting
• Ability to effectively prioritize workload and manage changes in direction
• Regularly reviews goals and objectives with supervisor

Physical Requirements:

• • • Must be able to work in an office environment with minimal noise conditions.
    • Must be able to work in Lab setting with exposure to Animals/biohazards / Chemicals (List specific Chemicals)
    • Must not have animal allergies to applicable species in this facility
    • Must be able to wear appropriate PPE
    • Must be able to work in environment with variable noise levels
    • Ability to stand /Sit/walk for long periods of time
    • Ability to Lift 10 lbs. routinely
    • Ability to crouch, bend, twist, and reach
    • Ability to push/pull 10 lbs. routinely/ often / occasionally
    • Clarity of Vision
    • Ability to identify and distinguish colors
    • Must be able to perform activities with repetitive motions
    • Ability to climb Ladders / Stairs / Scaffolding
    • Ability to work in variable temperatures high to freezing
    • Inside/outside working conditions
      

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability

This job description does not state or imply that the above are the only duties and responsibilities assigned to this position. Employees holding this position will be required to perform any other job-related duties as requested by Management.