The Scientist will represent nonclinical safety on drug discovery and development project teams. The position will require a strong scientific background and problem-solving skills. A fluid ability to work with multi-functional project teams is key. Reports into Director, Non-Clinical Safety.

Responsibilities

• Develop and execute nonclinical safety strategy to support candidate lead optimization efforts
• Conduct target safety assessments and develop de-risking strategies for any potential toxicity issues related to undesired or exaggerated pharmacology
• Design and oversee toxicology studies conducted at external CRO’s
• Analyze, interpret and present nonclinical safety findings to key internal stakeholders
• Collaborate closely with internal Discovery and Development colleagues on project teams

Qualifications

To perform this job successfully, an individual must be able to perform each essential duty. The requirements listed below are representative of the knowledge, skill, abilities and prior experience required.

• Ph.D. or equivalent in toxicology, pharmacology, or related disciplines
• 1-3 years of relevant experience post-degree, preferably in biopharmaceutical, CRO or government settings. Up to 2 years postdoctoral research experience in a relevant field would be considered contributory to the duration of experience requirement.
• Expertise in conducting both in vitro and in vivo toxicology studies
• Good communication, presentation, and technical writing skills
• This is a hybrid position, with a 3 day in the office expectation (South San Francisco).
• Experience in the design, execution, and oversight of Good Laboratory Practice (GLP) toxicology studies is preferred.

Pliant requires all new hires to be fully vaccinated prior to the first date of employment (subject to any legally required exemptions).