Preclinical
Only about one in 1,000 drugs progress from preclinical testing to human trials. Researchers now focus on building robust preclinical models to improve this statistic. Preclinical research tests drug safety before clinical trials. Determining endpoints in toxicology studies generates robust data for future studies. Learn the latest testing approaches in our preclinical webinars.
Innovative Testing Approaches
Historically, scientists performed toxicity testing in animal models. Now, they increasingly use in vitro systems. Our webinars cover best practices for PK/PD studies, ADME testing and developing humanized animal models and xenografts.
Advancing Disease Research and Drug Discovery
Preclinical models play a key role in disease research and drug discovery. They help identify new drug targets through high throughput screening. These models also optimize drugs for new and existing targets.
Cutting-Edge Technologies
Preclinical testing now goes beyond testing drugs on cells in a dish. New technologies create complex, disease-relevant models that mimic human systems. These include humanized animal models, organoids, patient-derived xenografts (PDX) and 3D cell cultures. Such models offer greater reliability and translatability to clinical settings.
Stay Informed
Xtalks brings the latest preclinical developments through webinars covering topics in cardiovascular research, COVID-19, the microbiome in cancer and inflammation, immunotherapies, lupus, rare diseases and more. Register for our on-demand and live preclinical webinars to gain insights from industry and academic experts.