Regulated digital polymerase chain reaction (dPCR), quantitative polymerase chain reaction (qPCR) and reverse transcriptase quantitative polymerase chain reaction (RT-qPCR) are extensively utilized to support biodistribution, vector shedding, gene expression, chimeric antigen receptor (CAR) T cell therapy and oncolytic viral bioanalytical studies.
In this presentation, the featured speakers will review the advantages and disadvantages of dPCR, qPCR and RT-qPCR as it relates to vaccine and biotherapeutic research. The featured speakers will also discuss the current method development and method validation best practices, context of use and level of regulatory compliance required to support bioanalysis in the pre-clinical and clinical settings.
Join this informative webinar to gain insights into the best use of PCR methods in the pre-clinical and clinical development of vaccines and other biotherapeutics.
Manisha R. Diaz, PhD, Associate Director of Research and Development, Eurofins Viracor BioPharma Services
Dr. Manisha Diaz is the Associate Director of Research and Development at Eurofins Viracor BioPharma. She has over eight years of experience in the pharmaceutical CRO industry. She leads in optimizing the quality and efficiency of R&D. Her wide range of experience includes developing immunoassays and viral molecular assays to support clinical trials. She has interest and expertise in viral shedding (qPCR, dPCR, and sequencing) and immune function assessment using ligand binding technology. Prior to joining Eurofins Viracor, Dr. Diaz was a Postdoctoral Associate in the Department of Molecular Biosciences at the University of Kansas where she investigated the regulation of bacterial autolysins. She received her PhD in Microbiology (Bacterial Genetics) from the University of Iowa and a Masters in Biological Sciences from Bowling Green State University.
Deepak Tomar, PhD, Senior Scientific Lab Lead, Eurofins Bioanalytical Services
Deepak Tomar serves as the Senior Scientific Laboratory Lead at Eurofins Bioanalytical Services. He obtained his PhD in Biochemistry from the All-India Institute of Medical Sciences in India. For his postdoctoral training, Deepak pursued molecular immunology at Emory University in Atlanta, focusing on single-cell emulsion PCR technology for generating monoclonal antibodies against diverse targets, including autoimmune and infectious diseases. Prior to joining Eurofins, Deepak gained valuable expertise at IDT, where he extensively contributed to the validation of new PCR/RT-PCR master mixes and worked with multiplex RT-PCR for virus detection. His research findings have been published in reputable international scientific journals and have been widely recognized and cited worldwide within the scientific community.
Erik Jerks, PhD, Director of Bioanalytical Services, Eurofins Bioanalytical Services
Erik Jerks, Director of Bioanalytical Services at Eurofins Bioanalytical Services, has over 20 years of pharmaceutical industry experience. Erik is a business-oriented manager skilled at operationalizing science and coordinating functional teams. He is LATG-certified, with extensive knowledge working within a GLP/toxicology laboratory. Erik is also a CLIA technical supervisor and a member of the Global CRO Council.
Who Should Attend?
This webinar will appeal to professionals working in a pharma, biotech, CRO, or public organization in the following roles:
- Sponsor and Scientist
- Principal Investigator
- Senior Scientist
- Study Director
- Heads of Research
Relevant areas of interest include:
- Vaccine and therapeutic pre-clinical and clinical space
- Quantification of pathogen loads
- Gene and micro-RNA expression analysis
- Oncology therapies
What You Will Learn
Attendees will gain insights into:
- The advantages and disadvantages of dPCR, qPCR and RT-qPCR
- Identifying the best practices and strategies for optimizing dPCR, qPCR and RT-qPCR assays in vaccine and biotherapeutic research
- The relevant recommendations related to dPCR / qPCR / RT-qPCR in pre-clinical and clinical settings
Eurofins BioPharma Services
The Eurofins BioPharma Services Network of Companies is a first-class biopharmaceutical outsourcing services partner (Contract Research Organization – CRO, Contract Development & Manufacturing Organization – CDMO), working with pharmaceutical, chemical, biotechnology, medical device and cosmetic clients. The network covers the whole chain of drug development thanks to an international network of laboratories and testing units with global reach, uniform QA systems and high-quality services. From compound discovery and clinical research through manufacture and release of commercial product and post approval/marketing, Eurofins BioPharma Services provides seamless, end-to-end solutions to help clients progress through the drug development cycle through a single, experienced provider. Our integrated solutions deliver the most comprehensive range of state-of-the-art analytical technologies with an expansive geographic reach in order to support our clients’ specialized testing needs and stringent quality and safety requirements around the world.