Fisetin: A Little-known Nutrient that Could Lead to Breakthroughs in Longevity & Cognitive Health

Food, Food Ingredients & Innovations,
  • Thursday, July 21, 2022

Advancement in nutrition and medical sciences have increased life expectancy in most developed countries. However, increased life expectancy brings associated aging problems in a significant proportion of the population. These include neurodegenerative diseases, Alzheimer’s disease, diabetes, osteoarthritis, atherosclerosis and vision problems. Recent research has identified the accumulation of senescent cells as a contributor to age-related issues. Here, the featured speakers discuss the potential benefits of a little-known nutrient called fisetin for tackling these issues.

Senescent cells are old cells with damaged DNA that have lost their ability to divide. Also known as “zombie” or “rogue” cells, senescent cells do not die; instead, they accumulate and inflame the cells and tissues around them. Cellular senescence weakens an organism over time by increasing its susceptibility to age-related diseases. This contributes to an organism’s slow decline and accelerates the progression of many age-related issues.


Fisetin is a potent, naturally occurring flavanol found in various fruits, vegetables and shrubs. For years, researchers have been studying its capacity to act as an antioxidant and reduce inflammation in the body. In more recent years, researchers have also discovered its benefits in healthy aging and cognitive function. Various studies demonstrate fisetin’s range of positive health effects, including its role as an antioxidant and senolytic.

Senolytics — compounds that eradicate senescent cells — help to prevent age-related disease, and even mitigate those that may have already developed. Studies have shown that fisetin is a very powerful senolytic, especially compared to other flavonoids.

Recently, there has been increased consumer interest in preventative selfcare related to healthy aging, and more specifically, cognitive function. With growing interest in functional products that can help with mental acuity, mood and protect neurological function, one of the challenges is finding ingredients that can both be effective and cross the blood-brain barrier to affect neurological function.

Fisetin has been shown to cross the blood-brain barrier, and research has suggested that it can mitigate oxidative stress within the brain — protecting neurological functions such as memory, cognition and neuron function. Fisetin presents these neuroprotective actions by interacting with and mitigating reactive oxygen species (ROS) which can cause inflammation and damage to cells. These wide range of actions suggest that fisetin can reduce the impact of age-related neurological diseases on brain function.

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Join this webinar to examine current consumer health trends related to healthy aging and cognitive health. Review the current scientific understanding around fisetin, its anti-aging and neuroprotective effects and future applications for this potent antioxidant senolytic.


Tom Vierhile, Innova Market Insights

Tom Vierhile, VP Strategic Insights, North America, Innova Market Insights

Tom Vierhile is Vice President of Strategic Insights North America for Netherlands-based Innova Market Insights. He has more than 20 years’ experience in packaged goods reporting and analysis. Based in Fairport, NY, he is a new Product Marketing Expert and has been quoted by Bloomberg, Ad Age, The Wall Street Journal and NPR. Tom has given presentations on new product trends at conferences in the US, Europe, Asia and South America. A regular contributor to Prepared Foods magazine, Tom has a bachelor’s degree in marketing from St. Bonaventure University and an MBA from the State University of New York at Buffalo.

Message Presenter
Erin Hopkins, Bioriginal Food & Science Corp.

Erin Hopkins, Director of New Product Development, Bioriginal Food & Science Corp.

Erin Hopkins is a Director of New Product Development with Bioriginal Food and Science in Saskatoon, SK, Canada. Erin has a Bachelor of Science in Agriculture (2014), and a PhD in Food Science (2019) from the University of Saskatchewan (USask). During this tenure, she had research published in more than 10 papers in peer reviewed scientific journals. Erin joined Bioriginal shortly after completing her doctorate as a Product Development Specialist and has recently moved into a director role. Her role at Bioriginal focuses on bringing new products to market and advising on scientific matters for customers and the company.

Message Presenter

Who Should Attend?

This webinar will appeal to senior-level professionals such as directors and managers within the dietary supplement and food & beverage industries:

  • Business Development
  • Product Development
  • Scientific/Technical Affairs
  • Research & Development
  • Product Innovation
  • Sales & Marketing
  • Marketing Managers
  • Product Managers

What You Will Learn

Join this webinar to learn about:

  • Current trends in healthy aging related to cognitive health
  • Published clinical data demonstrating the effects of fisetin’s health aging benefits, its mechanisms of action and its safety aspects
  • Fisetin’s wide range of actions and its ability to reduce the impact of age-related neurological diseases on brain function

Xtalks Partner


Bioriginal is a global leader in manufacturing natural nutritional foods, ingredients and supplements for food and beverage companies. For 25 years, Bioriginal has carved out a niche by scientifically combining ingredients from all over the world, directly from the source, to create innovative and efficacious solutions. Developing proprietary methods and systems, Bioriginal provides customized turnkey solutions for our customers that help them compete and win in a highly competitive space. Bioriginal’s wide portfolio includes plant- and marine-based oils, seeds & grains, protein products, nutraceuticals and botanical ingredients. Bioriginal is headquartered in Saskatoon, Canada with facilities throughout the USA, Europe and Asia. Bioriginal is a member of the Cooke family of companies.

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