Clinical Laboratory Technologist II/III

BostonGene

Posted on: March 30, 2026

Closing: April 29, 2026

Salary: Undisclosed

Position Type: Full Time

Job Description

Job summary

Perform high-complexity molecular testing in a CLIA/CAP-regulated environment, including DNA and RNA extractions, NGS library preparation, hybridization-based enrichment, and next-generation sequencing. This role operates with

increased independence and serves as a technical resource within the laboratory, supporting assay performance, troubleshooting, and continuous process improvement.

We are seeking a highly motivated, detail-oriented professional with strong technical expertise, a proactive mindset, and the ability to collaborate effectively across teams while driving high-quality laboratory operations.

The schedule required is Monday-Friday with rotating Saturdays.

Responsibilities

  • Independently perform and oversee high-complexity molecular workflows, ensuring accuracy, consistency, and adherence to SOPs
  • Operate, troubleshoot, and optimize quantification, sizing, liquid handling, and NGS instrumentation
  • Serve as a technical resource for junior staff, providing guidance, training, and support on laboratory processes and best practices
  • Lead or contribute to assay validations, verifications, and implementation of new technologies or workflows
  • Perform and review quality control data, identify trends, and escalate or resolve issues as needed
  • Drive continuous improvement initiatives to enhance workflow efficiency, data quality, and Turnaround Time (TAT)
  • Collaborate cross-functionally (e.g., Bioinformatics, R&D, Operations) to support process improvements and issue resolution
  • Utilize LIMS to manage, track, and ensure the integrity of sample processing and associated data
  • Ensure compliance with CLIA, CAP, GCLP, and internal quality standards, including rigorous documentation practices (GDP)
  • Participate in and contribute to SOP authoring, review, and revision to reflect process improvements and regulatory updates
  • Oversee inventory management and forecasting of reagents and consumables to support uninterrupted lab operations
  • Perform and/or coordinate routine and preventative maintenance of laboratory equipment; escalate complex issues to vendors as needed
  • Maintain a safe, organized, and audit-ready laboratory environment

Qualifications

  • Minimum BS in a Biological or Life Science.
  • Bachelor's degree in Biological Sciences or related field (Master's preferred for Tech III)
  • Tech II: 3-5 years of relevant experience
  • Tech III: 5+ years of experience with demonstrated technical leadership and ownership of workflows
  • Strong hands-on experience with molecular techniques, including NGS workflows
  • Experience working in a regulated clinical laboratory environment (CLIA/CAP/GCLP preferred)
  • Proven ability to troubleshoot complex technical issues and drive resolution independently
  • Demonstrated ability to train or mentor others and contribute to team development
  • Strong organizational skills with the ability to manage multiple priorities effectively
  • Excellent attention to detail and commitment to data quality and integrity
  • Strong communication and collaboration skills
  • Physical Requirements:

This position requires the ability to stand and move throughout the laboratory for extended periods of time. The role also requires the ability to lift and transport materials and equipment weighing up to 15 pounds.

BostonGene

Posted on: March 30, 2026

Closing: April 29, 2026

Salary: Undisclosed

Position Type: Full Time

Career Focus: Laboratory Technology

This role is part of a curated selection of life science opportunities featured on Xtalks. Employers may request edits or removal here.

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