Director, Nonclinical Safety

Relay Therapeutics

Posted on: February 7, 2025

Closing: March 09, 2025

Position Type: Full Time

Job Description

  • Develop and implement strategies to support lead optimization and candidate selection efforts of small molecules and targeted protein degraders
  • Conduct target safety assessments to assess the benefit-risk of targets early in the drug discovery process
  • Work closely with Nonclinical operations to coordinate, design, monitor and manage external toxicology studies
  • Represent Toxicology in multifunctional discovery and early development project teams; integrate, summarize and effectively communicate complex data
  • Collaborate with key stakeholders and project team members to support drug discovery and development
  • Contribute to the cross-functional review of regulatory documents and author and review Toxicology sections for relevant regulatory documents
  • Initiate, lead and champion innovations to ensure relevant cutting-edge science is applied to project-related issues
  • Contribute to a team culture that promotes fearlessness, inclusion, candor and craftmanship

Your Background

  • PhD in Toxicology, Pharmacology or related sciences (e.g, DVM) and a minimum of 10+ years of industry experience in Toxicology (DABT certification preferred)
  • Ability to work effectively with Discovery Research teams in support of small molecule and protein degrader lead optimization and development candidate nomination strategies
  • Strong knowledge in Toxicology study design, monitoring, data interpretation, and their integration in support of drug development.
  • Track record of applying a 3Rs-centered and welfare-oriented approach to animal-based research
  • Familiar with developing and managing relationships with CRO partners
  • Clear written and oral communication skills and the ability to distill complex data sets for team discussions and regulatory deliverables

Relay Therapeutics

Posted on: February 7, 2025

Closing: March 09, 2025

Position Type: Full Time

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