In Vivo Pharmacology runs pre-clinical studies for external customers in areas of Oncology, Neurobiology, Autoimmune Diseases. Working under limited supervision, the In Vivo Technologist II is fully proficient with latitude for independent judgement; performs advanced biomethods, including complex tasks, and highly developed procedures. Additional responsibilities include understanding study timelines and communicating issues effectively. The level II technologist is expected to proactively seek out new opportunities that will enhance the team such as serving as a mentor, checking for quality gaps, organizing lab spaces for inspections and audits and understanding scientific content. Staff members may be required to work weekend shifts, holidays, and overtime.

Working under limited supervision, the Preclinical Technologist I:

• performs proficiently regular and advanced wet lab procedures,
• may assist in mouse injection and phenotyping,
• understands project timelines,
• is able to communicate complex scientific results efficiently with peers and supervisors.

The technologist proactively seeks out new opportunities that will enhance the team such as

• checking for quality gaps,
• and organizing lab spaces for inspections and audits and

This position maybe required to work weekend shifts, holidays, and overtime.

Key Responsibilities & Essential Functions:

• Execution of drug formulation protocols, and drug administration to mice

• Wet lab molecular biology and biochemistry experiments such as gene expression/qPCR, protein analyses by Western Blot, blood cell/splenocyte isolation, FACS, immunoassays,

• Computer-assisted image analyses and data management

• Live animal phenotypic testing (eg. Electromyography, locomotor and behavioral testing)

• Adhere to all SOPs, policies and regulatory procedures

• Accurate data entry including lab IT systems and databases. Maintain appropriate documentation as required by protocols and SOPs.

• Training to perform above procedures to proficiency levels and/or participate in the development of new procedures.

• Lab Maintenance – Perform general lab sanitation, maintain consumables and reagents, and maintain equipment through calibration, validation and monitoring.

• Other duties as assigned

The wage range is $23.27-33.74 per hour. Pay will be determined based upon qualifications and experience.

Qualifications:

• BS degree with 1 year of applicable work experience or High School diploma with 3 or more years’ applicable work experience in a laboratory/animal care setting or all requirements for a Technologist II have been met.

• Demonstrated ability in execution and development of research protocols.

• Capable of performing a wide range of animal biomethods, and/or complex procedures.

• Lab equipment operation experience.

• Excellent communication and listening skills with proven ability to effectively communicate with others both verbally and in writing on scientific and technical topics,.

• Proven excellent writing skills.

• Excellent problem-solving skills and ability to work effectively in a team environment.
• Ability to work independently with minimal oversight. Ability to make decisions that adhere to all SOPs, policies and regulatory procedures.
• Able to work in in vitro and in vivo environments, especially with animal handling.
• Advanced computer skills in Word, Excel and statistical analyses, ability to develop technical documents and presentations

• Ability to work flexible shifts (evening/weekend/holiday)

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About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community.