Holistic Measures of Physical Functioning in Cancer: New Opportunities with Digital Health Technologies

Life Sciences, Clinical Trials, Patient Recruitment & Retention, Healthcare, Digital Health,
  • Friday, December 01, 2023

Discover an informative webinar delving into the pivotal role of digital health technologies in capturing meaningful aspects of health in individuals living with cancer. Individuals living with cancer experience severely impacted health-related quality of life. Their ability to carry out activities of daily living is impaired by cancer and its treatments. There are various methods of understanding how a patient feels and functions in the disease and treatment. Patient-reported outcomes (PROs) can provide direct information on cancer-related symptoms and functioning and measure the benefit/risk of treatment in drug development.

Objective measures of real-world physical behavior have the potential to complement established PROs and provide additional insights into daily functioning. These measures can be captured remotely and continuously using digital health technologies such as wearable sensors. Digital measures could aid in the development of treatments that improve the aspects of physical function that matter to individuals living with cancer but incorporating them in drug development necessitates an evidence-based approach and direct input from researchers, regulators and patients throughout the process.

Join this webinar as it will feature a panel of stakeholders from different perspectives (regulatory, pharma/industry, clinical and digital health) to discuss holistic measurement of physical function in cancer and opportunities for digital health technologies to provide value.


Suvekshya Aryal, VivoSense Inc.

(Moderator) Suvekshya Aryal, Research Scientist, VivoSense Inc.

Suvekshya Aryal is a Research Scientist at VivoSense, currently focusing on understanding patients’ experience with cancer and its treatment and developing digital measures of physical functioning for integration into clinical trials. Suvu holds a master’s degree in public health and epidemiology and extensive clinical research experience.

Message Presenter
Heather Leach, Colorado State University

Heather Leach, Associate Professor and Director of the Physical Activity for Treatment and Prevention Lab, Colorado State University

Dr. Heather Leach, an Associate Professor and Director of the Physical Activity for Treatment and Prevention Lab at Colorado State University, holds a BS in Exercise Science, an MS in Exercise Physiology, and a PhD in Kinesiology. She completed postdoctoral fellowship training in physical activity for cancer survivorship at the University of Calgary and holds certifications as a Clinical Exercise Physiologist and Cancer Exercise Trainer.

With over 15 years of experience, she specializes in promoting exercise among clinical populations and teaching exercise science-related courses. Her research, funded by organizations like the American Cancer Society and the National Cancer Institute, focuses on understanding the social ecologic determinants of physical activity, assessing the benefits for cancer survivors and translating intervention research into healthcare and community programs.

Message Presenter
Thomas Switzer, Genentech

Thomas Switzer, Digital Health Scientist, Research and Early Development, Genentech

Thomas Switzer is a Principal Scientist and the Lead for Digital Health in Genentech’s Research and Early Development informatics group (gRED ECDi). He focuses on developing technology platforms supporting molecule teams across Genentech’s early development portfolio. Tom has over 23 years of clinical development experience, including nine years of experience in developing and deploying digital technologies in clinical trials.

Beyond his daily responsibilities supporting ECD, he serves as a key Genentech representative in a variety of cross-industry digital health technology initiatives, including the Clinical Trial Transformation Initiative Digital Health Trials, the Digital Medicine Society and Transcelerate. He has been at Genentech since 2010 serving in a variety of roles within clinical development.

Message Presenter
Theresa Coles, Duke University School of Medicine

Theresa Coles, Assistant Professor, Department of Population Health Sciences, Duke University School of Medicine

Theresa Coles, PhD, is an Assistant Professor at Duke University School of Medicine’s Department of Population Health Sciences. As a health outcomes methodologist, she specializes in measuring and evaluating patient-reported outcomes (PROs) and other clinical outcomes assessments (COAs) to aid decision-making in healthcare delivery and clinical research settings. Dr. Coles’ research is centered on three key areas: (1) Enhancing the assessment of physical function and related concepts, (2) Improving the interpretability of PRO scores and (3) Designing and implementing screeners to improve patient-centered care by measuring what matters. Dr. Coles employs qualitative and quantitative psychometric methodologies to answer measurement questions.

Message Presenter

Who Should Attend?

This webinar will appeal to professionals in the following fields:

  • Drug developers
  • Health technology providers
  • Patients and caregivers
  • Healthcare practitioners
  • Pharmaceutical companies involved in digital innovation in clinical trials

What You Will Learn

Attendees will have the opportunity to hear from experts across diverse fields, who will emphasize the significance of comprehensive capture of physical functioning through direct patient input and patient-generated data, while also exploring how digital health technologies can enhance cancer treatments and patient outcomes.

Xtalks Partner

VivoSense, Inc

VivoSense, Inc., develops and validates real-world digital clinical measures and provides end-to-end services and solutions for their delivery in clinical trials. Our hypothesis driven framework provides analytical and clinical validation leading to FDA approval. VivoSense delivers novel digital biomarkers from wearable sensor data which constitute primary and secondary clinical endpoints in regulated international pharmaceutical trials. VivoSense is dedicated to improving patient clinical research and care.

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