How Principal Investigators Can Proactively Improve Patient Enrollment

Life Sciences, Clinical Trials, Patient Recruitment & Retention,
  • Tuesday, April 19, 2022

Insufficient patient enrollment is one of the primary reasons clinical trials fail. Direct mail, advertising and social media help raise awareness, but do they enroll enough qualified patients for every trial?

Principal investigators play a critical role in converting interested patients to enrolled, consented participants. Those who have established relationships with patients or who take the time to build those relationships have better odds of success.

For example, an infectious disease specialist at St. Vincent’s Ascension in Birmingham, Alabama, recruited a diverse group of 200 participants for a COVID-19 study at the height of the pandemic. He succeeded because he had built trust with his patients over many years, and because he worked for an organization with deep roots in the city.

Trust is only one part of a multifactored equation investigators can use to meet patient enrollment goals more consistently. Other elements involve a proactive approach to patient outreach, communication and engagement.

Register for this webinar to learn the following:

  • The benefits of a proactive approach and the pitfalls of a reactive approach
  • How trust between patient and physician improves enrollment and retention
  • How investigator engagement influences recruitment and retention
  • Tips for setting up investigators for success


Arnold Silva, Boise Kidney & Hypertension Institute, in partnership with Frenova

Arnold Silva, MD, PhD, Founding Physician Partner and Director of Clinical Research, Boise Kidney & Hypertension Institute, in partnership with Frenova

Dr. Arnold Silva is founding physician partner and director of clinical research at Boise Kidney & Hypertension Institute, in partnership with Frenova. Twice awarded for excellence in teaching at the University of Arizona, Dr. Silva served as a clinical assistant professor of medicine and taught in the areas of biology, biochemistry and physiology for California State University and the University of California. With over 30 years of experience in both basic science and clinical research, Dr. Silva has spent the past decade focused on bringing nephrology clinical trials to southern Idaho to benefit patients with kidney disease. He has helped facilitate studies involving anemia in chronic kidney disease and end stage renal disease, secondary hyperparathyroidism and hyperphosphatemia, diabetic nephropathy and adult polycystic kidney disease.

Message Presenter

Who Should Attend?

  • Principal investigators
  • Clinical operations executives
  • Site operations executives
  • Clinical research organization (CRO) program managers
  • Patient recruitment managers

What You Will Learn

  • Proactive patient recruitment tactics
  • Patient recruitment strategies for success
  • How to build trust between investigators and patients

Xtalks Partner


Frenova is a provider of clinical research and site management services with 25 years of experience in clinical research. Whether you want to conduct a study, seek guidance on your protocol design or access to patients around the world, Frenova provides the managed investigator sites, patients and data your clinical trial demands. Frenova, a company of Fresenius Medical Care, manages the world’s largest network of renal research assets, including over 550 principal investigators at more than 350 sites around the world. We also offer access to hundreds of thousands of patients with kidney disease, including CKD and ESRD. By pairing this extensive network with our clinical development and bioinformatics database and capabilities, Frenova easily determines protocol feasibility, drives patient recruitment/enrollment strategies and identifies the right sites for your study. We develop strategies that shorten your path to study completion, no matter the scope of your needs.

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