For decades, many groups around the world have pursued the isolation and genetic analysis of circulating fetal cells from maternal peripheral blood as an improved form of noninvasive prenatal testing. However, the exceeding rarity of these cells in the blood of pregnant women has proven a challenging obstacle in the establishment of a reliable test methodology.
Luna Genetics has overcome this challenge using a unique combination of robust immunostaining, microfluidic enrichment, automated microscopy and single cell isolation. The noninvasive prenatal testing method was validated with over 200 high-risk cases undergoing chorionic villus sampling (CVS) or amniocentesis, along with 158 low-risk cases not undergoing CVS or amniocentesis. The Luna Prenatal Test showed near-perfect concordance with the CVS and amniocentesis results, and the few discordant cases were consistent with current knowledge of confined placental mosaicism. Various genetic abnormalities were detected by the Luna Prenatal Test over the course of the study, including common trisomies, rare autosomal trisomies, microdeletions, microduplications and confined placental mosaicism.
Register today to learn about a breakthrough in the reliable isolation and successful analysis of circulating fetal cells for noninvasive prenatal testing early in pregnancy. The webinar will include the path taken to establish the Luna Prenatal Test methodology, data from key validation cases and the future trajectory of the test.
Disclaimer: Namocell products are for research use only; not for diagnostic purposes.
Mason Ouren, R&D Scientist, Luna Genetics
Mason Ouren is a curious and innovative researcher with a passion for improving human health. He received his BS in genetics and genomics from the University of Texas at Austin and began his professional scientific career at Luna Genetics in December 2019. Mason has assisted in the development, validation and clinical implementation of a revolutionary noninvasive cell-based prenatal test during his time at Luna Genetics. He now leads R&D efforts at Luna Genetics and specializes in cell separation and assay development.
Who Should Attend?
Professionals with interests in:
- Single Cell Genomics/Proteomics
- Prenatal genetics
- Cell-based biomarkers
- Rare cell isolation
And the following job titles:
- Research Associate
- Principal Investigator
- Lab Manager
- VPs of R&D
What You Will Learn
Attendees will learn:
- Historic challenges to the establishment of a noninvasive cell-based prenatal test
- How the Luna Prenatal Test isolates and analyzes single circulating fetal cells early in pregnancy
- How the Luna Prenatal Test makes a positive difference in patient care and reproductive health
Namocell, a Bio-Techne brand, is a leading provider of innovative single cell sorting and dispensing platforms to empower single cell research and therapeutics development. Namocell’s single cell dispensers are the fastest and easiest way to sort and isolate single cells and enable users to accomplish single cell sorting and dispensing in one step in a way that is gentle to live cells. Namocell serves researchers and scientists in a wide range of applications, including cell line development, CRISPR and cell line engineering, single cell genomics and proteomics, cell and gene therapy, antibody discovery, rare cell isolation, and synthetic biology.