Unparalleled Peptide Library Production: Automating High-throughput Peptide Synthesis and Purification

Life Sciences, Laboratory Technology,
  • Tuesday, January 16, 2024

Discover a groundbreaking webinar delving into automated plate-based unparalleled peptide library production. Peptides and other beyond-rule-of-five compounds have become thoroughly entrenched within the medicinal chemist’s modality toolbox. Principally, this is motivated by their potential for antibody-like target affinity and specificity coupled with the potential for cell permeability.

With the advent of unbiased screening technologies, incorporating both natural and non-natural amino acids, the propensity for pursuing a discovery project with these compounds has become more tractable. Once hits are selected from the primary screen, the chemist’s job truly begins.

Automated parallel peptide synthesizers enable the preparation of hundreds to thousands of peptides simultaneously, further driving a peptide drug discovery campaign. However, solutions that address the onerous downstream and high-throughput workup requirements for those peptide libraries are limited.

The featured speaker will present data demonstrating a disruptive approach to downstream handling of peptide libraries that replaces traditionally manual processes without compromising peptide integrity and product yield. All the while potentially improving purity before delivery to downstream biological assays.

As technologies for unbiased peptide library screening incorporating both natural and non-natural amino acids have evolved, the appetite for large and synthetic peptide libraries has increased. Therefore, demanding changes to the traditional workflow to avoid significant productivity bottlenecks.

New technologies must consider fundamental standards from the established methodologies before widespread acceptance can be achieved. Join this webinar to gain insight into the uncompromising criteria and understand how those demands are addressed in this newly proposed peptide library workflow.

Gyros Protein Technologies and Biotage partner to advance peptide purification efficiency with new automated solution

PeptiRen-96 C18 100 Å 500 mg Plates (biotage.com)

Parallel Peptide Workflow (biotage.com)


Elizabeth Denton, Biotage

Elizabeth Denton, PhD, Senior Scientist, Biotage

Elizabeth Denton is the Sr. Peptide Scientist at Biotage where her role includes the development of new tools and methods that scientists around the world use to improve workflow efficiency to synthesize and purify peptides which are delivered for downstream evaluation. She completed a PhD in Chemistry at Yale University under the supervision of Alanna Schepartz, identifying and evaluating peptides designed to stimulate the activation of various proteins and signaling cascades.

Message Presenter

Who Should Attend?

This webinar will appeal to professionals in the peptide synthesis in the following roles:

  • Director/group leader
  • Research Associate/Chemist/Fellow/Scientist
  • Scientific Associate/Developer I
  • Senior Chemist/Director/Principal Scientist/Scientist
  • VP Chemistry/Discovery Chemistry/Laboratory Operations/Operations

What You Will Learn

Attendees will gain insights into:

  • How plate-based workflows can simplify compound management and factors to consider optimizing this style of workflow
  • How to minimize pre- and post-synthesis plate-based compound handling steps with complementary tools
  • Why scientists should eliminate onerous, manual peptide workup steps from the workflow
  • How to gain productivity by combining complementary tools designed for peptide workflows

Xtalks Partner


Biotage is a Global Impact Tech Company committed to solving society’s problems. We offer workflow solutions and products to customers in drug discovery and development and diagnostics, analytical testing and water and environmental testing.

Biotage is contributing to sustainable science with the goal to make the world healthier, greener and cleaner – HumanKind Unlimited.

Our customers span a broad range of market segments including pharmaceutical, biotech, diagnostic, contract research and contract manufacturers as well as clinical, forensic and academic laboratories in addition to organizations focused on food safety, clean water and environmental sustainability.

We offer workflow solutions and products to customers in Peptide Synthesis, Drug Discovery and Development, and Analytical Testing. Our range of tools increases speed and efficiency of all steps in the peptide synthesis workflow, while improving the quality of peptides synthesized.

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