Job Type

Full-time

Description

BBOT is a clinical-stage biopharmaceutical company advancing a next-generation pipeline of novel small molecule therapeutics targeting RAS and PI3K malignancies. BBOT has the goal of improving outcomes for patients with cancers driven by the two most prevalent oncogenes in human tumors. For more information visit BBOTx.com

Who You Are

This is an exciting opportunity for a highly motivated Toxicologist with a strong background in drug development. We are looking for a talented and enthusiastic individual who thrives in a collaborative, fast-paced, and growing environment to join our team as an Associate Director-Director. As a key member of the Toxicology Department, you will:

Responsibilities

• Lead and own all in vitro and in vivo non-clinical toxicology activities (non-GLP & GLP) for multiple programs. Design and communicate customized toxicology strategies for each program. Currently, all programs involve small molecules for oncology indications
• Serve as the toxicology representative: attend program meetings, collaborate with cross-functional team leads (e.g., DMPK and pharmacology), and guide project team leaders regarding toxicology and safety plans and timelines
• Plan, design, and oversee the execution of all outsourced CRO collaborations for toxicology and safety studies
• Manage, edit, and finalize collaborators' (CRO) study reports in a timely manner
• Analyze, interpret, present, and communicate all preclinical toxicology and safety study findings
• Make key recommendations to project teams for mitigation strategies and next steps
• Author high-quality regulatory documents to support filings such as IND, CTA, NDA, and IB
• Be an integral part of BBOT's culture: Hope through rigorous science

Requirements

Education and Qualifications

• A highly motivated, entrepreneurial, and committed individual with excellent communication and organizational skills
• Ph.D. in Toxicology, Pharmacology, Biology, or a related field; DABT preferred but not required
• 5+ years of professional experience in toxicology research or drug development in an industry setting; small molecule experience required. Experience working with CROs in the US, Canada, EU, and Asia

Why Join Us?

• Join a fast-paced, mission-driven biotech team focused on delivering transformational therapies
• Competitive salary, benefits, and meaningful equity participation in a public company

Compensation

BBOT considers a variety of factors when determining base compensation, including experience, skills, education, qualifications, and geographic location. Actual compensation will vary, and it is not typical to be hired at or near the top of the range for the role.

Base compensation is part of a robust total rewards offering at BBOT. Additional total rewards elements include annual bonus, stock-based long-term incentives, medical, dental, and vision benefits, retirement, wellness stipend, and flexible time off.

Salary Description

$181,900 - $239,700 in the San Francisco Bay Area