Director, Clinical AI Technologies

Structure Therapeutics

Posted on: April 15, 2026

Closing: May 15, 2026

Salary: 237,000.00 - 285,000.00 per year

Position Type: Full Time

Job Description

About Us:

Structure Therapeutics develops life-changing medicines for patients using advanced structure-based and computational drug discovery technology. The company's platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical-stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions.

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location. Reporting directly or operationally into the VP, Clinical Operations, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration

Position Summary:

The Director of Clinical AI Technologies is responsible for translating clinical operation needs into AI-driven solutions to lead the strategy, implementation, and scaling of artificial intelligence (AI) solutions that enhance the execution and performance of clinical trials. This role focuses on embedding AI into day-to-day Clinical Development Operations to improve study delivery, site performance, patient enrollment/engagement/retention, and data quality. As a leader within Clinical Development Operations, you will transform "AI potential" into "operational performance."

Job Responsibilities:
  • Evaluate, design and execute a roadmap/ framework for AI integration across Clinical Development Operations, prioritizing high impact areas
  • Identify and prioritize AI use cases to improve trial execution (e.g., site activation, enrollment, monitoring, issue detection). Embed AI tools into core Clinical Operations workflows, ensuring they are user-friendly for Clinical Trial Managers (CTMs) and Clinical Research Associated (CRA)s.
  • Define and track KPIs to measure the ROI of AI implementations
  • Collaborate with cross-functional teams (Clinical, Clinical science, IT, Quality, Regulatory, etc) to ensure alignment with AI solutions/ initiatives and integrate with existing programs
  • Oversee vendor evaluation, selection, and management for AI-enabled clinical technologies including AI vendors and technology platforms. Manage these partnerships to ensure AI outputs are validated and actionable.
  • Facilitate knowledge transfer and best practices for AI applications within clinical operations settings
  • Drive adoption through training, change management, and stakeholder engagement
  • Establish Standard Operating Procedures (SOPs) and governance for AI use in clinical development operations, including validation, performance monitoring, and documentation
  • Ensure compliance with GCP/GxP, regulatory requirements, and internal quality standards
  • Continuously assess emerging technologies and recommend innovations to improve operational performance

Education/Qualifications:
  • BS or advanced degree in Life Sciences, Computer Science, Data Science, or technical field
  • Minimum 8 years of experience in within pharma, biotech, or CRO settings, including 5+ years of experience in AI/ML (machine learning), advanced analytics, or digital health initiatives
  • Experience leading or participating in AI projects within clinical or biomedical domains.
  • Understanding of clinical trial processes with skills to translate them into AI solutions.
  • Background in AI, machine learning, and data science, with practical experience in clinical applications.
  • Strong interpersonal and communication skills for effective cross-functional collaboration.
  • Familiarity with regulatory compliance requirements for AI in clinical trials.
  • Demonstrated ability to contribute to innovation and change within a matrixed organization.

Structure Therapeutics Inc. is an Equal-Opportunity Employer.

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $237,000 - $285,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate's geography, qualifications, skills, and experience.

At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.

Notice to Recruiters/Staffing Agencies

Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees.

We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.

Structure Therapeutics' receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.

Fraud Alert

To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page atBambooHR.

Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.

Structure Therapeutics

Posted on: April 15, 2026

Closing: May 15, 2026

Salary: 237,000.00 - 285,000.00 per year

Position Type: Full Time

Career Focus: Artificial Intelligence

This role is part of a curated selection of life science opportunities featured on Xtalks. Employers may request edits or removal here.

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