Principal Software Engineer

Element Science

Posted on: April 18, 2026

Salary: Undisclosed

Job Description

Element Science, Inc. is a medical device and digital health company redefining how patients with heart disease are monitored and treated as they transition from the hospital to the home. Our mission is to improve outcomes for patients at risk of life-threatening cardiac events through innovative solutions at the intersection of clinical-grade wearables, advanced algorithms, and therapy delivery.

We are entering an exciting phase of growth as we move from development into early commercialization. Our approach combines hardware, software, and services to deliver a more personalized and seamless patient experience-designed with both patients and clinicians in mind. Our product, a wearable patch defibrillator, is designed for patients with a temporary elevated risk of sudden cardiac arrest, addressing a significant and underserved population of over 500,000 patients in the U.S. By focusing on comfort, usability, and clinical effectiveness, we aim to transform the standard of care during this critical period. Headquartered in the San Francisco Bay Area, Element Science is backed by leading healthcare and technology investors, including Third Rock Ventures, GV (Google Ventures), Deerfield Healthcare, Qiming Venture Partners USA, Cormorant Asset Management, and Invus Opportunities.

SUMMARY OF ROLE:

We are looking for a hands-on Principal Software Engineer to drive the development of our software ecosystem comprising of Cloud services and client applications to support our life-saving wearable medical devices. These Cloud services include a data platform containing data from our wearable medical devices that provide critical insight into product usage, patient experience, potential improvements, and new products. The ideal candidate thrives in a commercial start-up environment that is scaling rapidly, can help drive strategic planning of software-related business needs, and can execute software design, development, and testing.

This is a hybrid role based in our San Francisco or Redwood City, CA office, with a planned transition to our Redwood City, CA office within the year. We are in office Tuesday through Thursday. Candidates located outside of the Bay Area may be considered for a remote arrangement, if able and willing to travel to the Bay Area.

RESPONSIBILITIES:
  • Lead the architecture, design, implementation and testing of a reliable, scalable, secure and HIPAA compliant software ecosystem including Cloud services for receiving, processing, and storing relevant data from multiple sources, and clients such as mobile, desktop and web applications.
  • Perform hands-on software development for Cloud services and client applications as needed.
  • Collaborate with Product Management, Firmware Engineering, Algorithms & Data Science, and Information Technology teams to define and deliver business value.
  • Drive data platform design and implementation for wearable device and business operations data, including storage, transformations, and interfaces with machine learning algorithms.
  • Define technical content and deliver software design documentation covering architecture, design, requirements, verification and system/cybersecurity risks.
  • Drive technical roadmap, software quality and best practices in collaboration with software team and software management.
  • Provide technical guidance and mentorship across the software engineering team.
  • Manage software projects as needed.

QUALIFICATIONS:
  • B.S. in Computer Science, Engineering, or equivalent.
  • 8-12 years minimum of relevant industry experience with 2 years minimum in technical leadership. Medical device industry experience preferred.
  • Experience with architecture, design and implementation of Cloud services following best practices on reliability, security, operations, performance, and cost. HIPAA compliance experience is preferred.
  • Extensive hands-on experience with development of Cloud services using Python, Java, or C#. Strong knowledge of AWS is highly desirable.
  • Extensive knowledge of REST and SOAP, as well as SQL and NoSQL databases and services.
  • Experience with JIRA and Git based repositories is highly desired.
  • Experience with leading software projects within a cross-functional team environment.
  • Preferred experience with development of data platforms for aggregation, processing and display of device and business systems data to drive design changes and business decisions.
  • Preferred experience with developing or interfacing with machine learning algorithms.
  • Preferred experience with development of iOS and Android mobile applications using native or cross-platform frameworks.
  • Preferred experience with system design method from IDesign.
  • Preferred familiarity with medical system integration (EMR, for example) using standards such as HL7 FHIR.
  • Excellent written and verbal communication skills.

BENEFITS:

Element Science offers a very competitive salary and benefits package including, but not limited to:
  • Stock Options
  • 90% employer-paid medical, dental, and vision insurance
  • Company-paid Basic Life Insurance
  • 401(k) retirement plan (Traditional and Roth)
  • Competitive Paid Time Off
  • Paid Holidays
  • FSA (Flexible Spending Accounts)
  • HSA (Health Savings Account)
  • Employee Assistance Program through PEO

The salary for this exempt-level position will be based on experience and qualifications within an established pay range.
  • Pay range: $190,000 - $200,000

Element Science is an Equal Opportunity Employer. All candidates will be evaluated on the basis of their qualifications for the job in question. We do not base our employment decision on an employee's or applicant's race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), political affiliation, military service, or other non-merit-based factors prohibited by local, state, or federal law.

In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. We are not able to sponsor individuals for employment visas for this job.

At this time, we are unable to offer relocation assistance at Element Science.

Element Science

Posted on: April 18, 2026

Salary: Undisclosed

Career Focus: Engineer

This role is part of a curated selection of life science opportunities featured on Xtalks. Employers may request edits or removal here.

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