We are a dedicated group of scientists, physicians, and businesspeople working together toward one goal: to discover and develop therapies that can unleash the power of the body's immune system to treat and potentially cure cancer. We are passionate about the work we do every day at Agenus to deliver on the promise of immuno-oncology. If you're looking for an inspired environment, passionate colleagues, and a culture that nurtures learning, innovation and team success, we invite you to join us.

The Opportunity

Agenus is seeking an exceptional Senior Executive Assistant to join the Office of the CEO and work closely with the Chairman/Chief Executive Officer.

This is far more than a traditional executive assistant role. As part of a small, high-performing team, you will gain firsthand exposure to the leadership and operations of a Nasdaq-listed biotechnology company. You will work in the Office of the CEO and interact with senior executives, Board members, investors, business partners, and other key stakeholders.

You will be trusted with significant responsibility, encouraged to take ownership, and given the opportunity to expand your skills and progressively assume greater responsibilities. This position reports to the Director of Operations of the Office of the CEO, who will provide training and mentorship, with both roles working closely together to provide coverage and support.

This is an ideal opportunity for an experienced executive assistant who wants to expand beyond traditional administrative responsibilities and continue to build a career in executive operations and corporate leadership.

Key Responsibilities

Executive & CEO Support

• Manage a complex, high-volume executive calendar across multiple time zones.
• Coordinate domestic and international travel, itineraries, and real-time changes.
• Serve as a trusted point of contact for internal and external requests.
• Manage communications, correspondence, follow-up, and action items.
• Anticipate needs, identify potential issues, and proactively resolve them.

Personal & Confidential Support

• Provide discreet administrative support for select personal commitments and appointments.
• Handle sensitive business and personal information with exceptional judgment and confidentiality.

Office of the CEO Operations

• Support the day-to-day operations and priorities of the Office of the CEO.
• Manage expenses, memberships, subscriptions, renewals, and other administrative responsibilities.
• Support the CEO's involvement with affiliated companies, philanthropic organizations, and other initiatives.
• Provide coverage for the Director, Operations, during absences.
• Identify opportunities to improve processes, increase efficiency, and leverage technology and AI.

Board, Leadership & Stakeholder Support

• Coordinate Board meetings, leadership meetings, investor meetings, partner meetings, and executive visits.
• Manage travel, accommodations, agendas, presentations, briefing materials, and meeting logistics.
• Coordinate executive dinners, events, and high-profile engagements.
• Build professional relationships with Board Members, investors, executives, and external partners.

What You Bring

• 5+ years of executive support experience, supporting a C-suite executive.
• Experience in a public company, biotechnology, pharmaceutical, life sciences, financial services, or similarly fast-paced environment preferred.
• Exceptional organizational skills and attention to detail.
• Proven ability to manage complex calendars, international travel, and high-level meetings.
• Excellent written and verbal communication skills.
• Confidence interacting with senior executives, Board Members, investors, and external stakeholders.
• Exceptional judgment, discretion, and ability to prioritize independently.
• Highly proactive, resourceful, adaptable, and remain calm under pressure.
• Strong Microsoft 365 skills; ability to quickly learn new systems and technologies.
• Comfortable using AI tools such as Microsoft Copilot, ChatGPT, or Claude to improve productivity and executive support.
• Bachelor's degree preferred.
• Curiosity and enthusiasm for learning how a high-level executive office and public company operate.

Location and Schedule

• Onsite at the Lexington, MA headquarters, Monday through Friday. Core hours are 8:00 AM to 5:00 PM.
• The CEO hosts dinners and events regularly, typically 5:00 to 7:00 PM; the Senior Executive Assistant is expected to be available for these. Occasional weekend work for travel changes and time-sensitive matters.
• Occasional travel to the company's New York office.
• The office is dog-friendly; a dog is present regularly.

Why This Is a Great Career Opportunity

This position offers an unusual opportunity to learn from senior leadership, become an essential member of the Office of the CEO, broaden your professional skill set, and build a career at the highest levels of the organization.

You will have the opportunity to:

• Work directly with the Chairman and CEO of a Nasdaq-listed biotechnology company.
• Gain exposure to Board relations, corporate strategy, investor interactions, and executive decision-making.
• Develop relationships with senior executives, Board Members, investors, and business partners.
• Take ownership of increasingly complex responsibilities and projects.
• Develop expertise in executive operations, corporate communications, event management, technology, and AI-enabled productivity.
• Learn from experienced professionals in a collaborative, high-performing environment.

The targeted salary range for this position is $80,000 - $113,000 per year. Agenus is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offered is commensurate with Agenus's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, critical needs of the role, and internal equity.

#LI-JW1 #LI-Onsite

Learn More About Agenus

Explore our innovative pipeline and connect with us on LinkedIn.

Why You'll Love Working at Agenus

We're proud to offer a comprehensive and inclusive benefits program designed to support your well-being, growth, and life outside of work:

• Medical, Dental & Vision Coverage - Competitive options for both US & UK employees
• Flexible Spending Accounts - For healthcare and dependent care expenses (US)
• Flexible Vacation Plan - We believe time away leads to better thinking and innovation.
• Care.com Memberships - Support for family care (US)
• Education Assistance Program - Invest in your learning and development (US)
• 401(k) Match
• Employee Stock Purchase Plan
• Employee Assistance Program (EAP) - Resources for mental health, well-being, and life support
• Reward & Recognition Program - Celebrate contributions that move the mission forward

What We Believe

• Patients First. We're here to make a difference-for every cancer patient.
• Bold & United. Big goals require strong teams.
• Integrity Always. Respect and honesty guide everything we do.
• Own It. We take responsibility-for results and how we achieve them.
• Always Learning. Curiosity drives innovation.
• Bring Your Best. Every day matters.