Position Summary

The Vice President of Biometrics will lead MBX Biosciences' biometrics function, overseeing biostatistics, statistical programming, and data management to support clinical development programs from early-phase through regulatory submission. This strategic role ensures the integrity, quality, and compliance of all clinical trial data and analyses while driving innovation in data strategy and statistical methodologies. Reporting into our Chief Medical Officer, this individual will serve as a key member of the Clinical leadership team, partnering closely with Clinical Development, Clinical Operations, Regulatory Affairs, and other functions to enable data-driven decision-making and successful product development.

Key Responsibilities

• Lead and build the Biometrics function, including biostatistics, programming, and data management, ensuring high-quality deliverables across all clinical programs.
• Oversee design and implementation of statistical methodologies for clinical trials.
• Ensure high quality and compliant biometric deliverables.
• Collaborate with cross-functional teams on protocols, statistical analysis plans, and data processes.
• Execute statistical analysis plans, ensuring statistical integrity and data consistency.
• Establish SOPs and best practices for innovative biometric strategies.
• Establish and maintain vendor partnerships ensuring quality and timely delivery of outsources biometrics activities.
• Support regulatory submissions and represent the company in agency interactions.
• Champion continuous improvement to enhance processes, systems, and compliance standards across the Biometrics function and organization.
• Other responsibilities as assigned.

Qualifications

• Advanced degree (PhD or MS) in Biostatistics or related field
• 15+ years of biometrics experience within the biotech or pharmaceutical field.
• Proven track record of leading, building, and managing teams.
• Deep knowledge of clinical trial design, regulator requirements, and statistical software.
• Excellent problem-solving skills, strategic thinking, and ability to work in a fast-paced, collaborative environment.
• Outstanding scientific leadership and collaboration skills.
• Outstanding interpersonal skills, self-awareness, and ability to manage team dynamics.

Travel

You will be expected to travel periodically based on the needs of the business to the extent requested by the Company including attendance at Together Weeks, Together Days and functional meetings as requested by the Company.

Company Overview:

MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP™ platform, for the treatment of endocrine and metabolic disorders. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company's pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. The Company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the Company website at www.mbxbio.com and follow it on LinkedIn.

EEO Statement:

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.