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Biomarkers

Our biomarkers webinars cover topics such as proof-of-concept, validations and imaging methods.

Biomarkers are measurable signs, usually biological molecules, that indicate a normal or disease state. They serve as surrogate measures of disease progression when we cannot directly measure the condition. Biomarkers also help determine an individual’s disease risk, enabling early interventions. In drug development, changes in biomarker levels help assess a therapy’s efficacy.

Regulators like the US FDA now accept biomarkers as endpoints in late-stage clinical trials and have approved some therapeutics based solely on these measures. However, drug developers must later prove that their therapy offers clinical benefits to maintain its approved status.

Clinicians use biomarkers in areas such as oncology, cardiovascular health and CNS conditions. Many biomarkers come from biological samples — serum, blood, cerebrospinal fluid or urine — while others rely on imaging techniques.

Liquid biopsy development remains an exciting, growing research area. Liquid biopsies use biomarkers to diagnose and monitor diseases. For cancers, researchers focus on circulating tumor cells (CTCs) and cell-free tumor DNA (ctDNA) as key biomarkers.

Xtalks hosts webinars on this dynamic research area. Explore presentations and articles on biomarkers and select from our recorded and upcoming biomarkers webinars at Xtalks.com.

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