Adapting IRT Resupply Algorithms to Balance Risk and Cost

Life Sciences, Clinical Trials, Pharmaceutical, Pharma Manufacturing & Supply Chain,
  • Tuesday, November 19, 2024

In clinical trials, managing investigational medicinal product (IMP) supply is critical to ensuring trial success. The interactive response technology (IRT) site resupply algorithm is a key component of this process, designed to balance two major considerations: risk (the security of IMP supply) and cost (associated with IMP waste and distribution).

While traditional IRT platforms generally rely on a standard resupply algorithm that combines buffer stock levels with predictable demand forecasting, this approach may not be optimal for every clinical trial. Each trial has a unique set of factors influencing the optimal resupply strategy, including trial design, patient enrollment rates, geographic distribution and supply chain complexities.

Advanced IRT and randomization and trial supply management (RTSM) platforms offer a more flexible solution by supporting a portfolio of resupply algorithms, allowing sponsors and vendors to collaborate in identifying the algorithm that best suits the needs of a particular trial. By leveraging the sponsor’s deep knowledge of the trial and the RTSM vendor’s expertise in resupply capabilities, the ideal balance between risk and cost can be achieved. This collaboration is essential to tailoring the resupply strategy to the specific demands of each study, reducing IMP waste, lowering distribution costs and maintaining a secure and efficient supply chain.

This session will explore the benefits of using advanced RTSM systems to customize site resupply algorithms, highlighting the critical role of sponsor-vendor collaboration. Attendees will gain insights into how different resupply strategies can impact trial outcomes and learn best practices for implementing a more flexible and efficient approach to RTSM site resupply management.

Register for this webinar to learn how to optimize a clinical trial’s resupply strategy and improve overall trial efficiency.

Speakers

Benjamin Etschmann, 4G Clinical

Benjamin Etschmann, Senior Forecasting Services Lead, 4G Clinical

Benjamin Etschmann has spent more than 10 years in clinical trial supply management in various roles, including operational trial supply logistics management and trial supply setup management. However, his primary focus has been in IRT management and demand forecasting using dedicated stochastic simulation tools. In his current role, he consults clients and internal teams on probabilistic site and depot demand forecasting in IRT.

Message Presenter
Conor Hayes, 4G Clinical

Conor Hayes, Client Services Lead, 4G Clinical

Conor Hayes is Client Services Lead at 4G Clinical and brings a decade of experience in clinical research across diverse roles. With more than four years at 4G Clinical, Conor specializes in collaborating with study teams to translate protocol and study requirements into effective Randomization and Trial Supply Management (RTSM) systems. He holds a BA in Neuroscience and a MSc in Biotechnology and Business, combining scientific expertise with expert knowledge to support the successful delivery of clinical trials.

Message Presenter

Buz Hillman, Associate Director, Strategic Management and Systems Discovery, Product Development & Supply, Johnson and Johnson

Buz is a seasoned expert in supply chain management, with over 40 years of experience in the healthcare sector. He is currently responsible for clinical supply forecasting systems and dashboards. In recent years, he has developed innovative approaches to clinical supply forecasting, IWR supply management, and waste reduction. He has also made significant contributions in data mining, wrangling, and visualization, identifying numerous opportunities to reduce risk and waste. These efforts have fundamentally transformed the clinical supply operating model at J&J. His deep commitment to enhancing healthcare supply chains continues to drive meaningful impact across the industry, setting new standards for efficiency and sustainability.

Message Presenter

(Moderator) Libbi Rickenbacher, Sr. Director of Product Strategy and Partnerships, 4G Clinical

Libbi Rickenbacher is the Sr. Director of Product Strategy and Partnerships at 4G Clinical. She has over 15 years of experience in the field of life sciences and is an e-clinical randomization and trial supply management (RTSM) solutions subject-matter expert. Libbi holds a BA in both Neuroscience and Psychology and a Doctorate (PhD) in Neuroscience.

Message Presenter

Who Should Attend?

The webinar will appeal to clinical research professionals with the following job titles or functions:

  • Clinical Supply Managers
  • Clinical Operations Managers
  • Procurement
  • Clinical Demand Planners

What You Will Learn

Attendees will gain insights into:

  • The importance of customizing RTSM site resupply algorithms to balance IMP supply security and cost
  • How advanced RTSM platforms enable sponsors to choose from a portfolio of resupply strategies tailored to individual trial needs
  • The critical role of collaboration between sponsors and RTSM vendors in optimizing site resupply algorithms
  • Best practices for selecting and implementing the most effective resupply strategy to reduce waste and costs while ensuring supply security

Xtalks Partner

4G Clinical

4G Clinical’s suite of innovative RTSM and clinical supply optimization software provides the right-sized support for any phase or trial complexity. At 4G Clinical, all studies are supported by a team of RTSM experts to advise trial teams on the best path forward. Our operations team distinguishes itself through their extensive industry expertise and deep understanding of trial designs and mid-study adjustments. 4G Clinical is committed to helping sponsors and CROs follow the science, wherever it may lead, as quickly and as safely as we can. While we will not discover the next novel compound in the lab, we are doing our part by leveraging our extensive experience and technological innovations to bring speed and agility to clinical trials. As a critical partner throughout clinical development, we can help you seamlessly transition and scale your trials through both protocol and supply complexities to help bring crucial medicines to those who need them, faster. To learn more about how we are tackling the bottlenecks in clinical trials through our innovative solutions, Prancer RTSM® and 4C Supply®, visit us at www.4gclinical.com.

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