Fluorescently-Labeled Peptides – Choosing the Best Dye and Designing the Best Peptide

Fundamental Research, Life Sciences, Preclinical,
  • Tuesday, October 23, 2018

Peptides fulfill numerous important tasks in nature. The investigation of such peptides in their natural environment is complex and requires specific techniques such as confocal microscopy. In order to study peptides with a confocal microscope, the peptide needs to be labeled with a fluorescent dye. A multitude of fluorescent dyes have been developed over the last decades, and are commercially available as starting materials for the synthesis of fluorescent peptides.

In this webinar, the speakers will provide an overview of known dye labels and highlight new developments in this field (e.g. dyes suitable for the study of complex processes, such as receptor-ligand interactions or the visualization of cellular structures). The speakers will also illustrate how to compare the performance of individual dye labels and give an overview over the commercially available options.

During the webinar, you will learn how to design the right substrate for your scientific application and how to attach the correct dye to the peptide sequence. In addition, you’ll get an overview of different synthetic methods as well as common pitfalls in the design of fluorogenic substrates. For more routine analyses, different decision pathways for the choice of substrates and dye labels will be discussed. The speakers will also demonstrate the use of an innovative new dye selector, which allows you to find suitable substrates for your required spectroscopic properties.

Speakers

Dr. Susanne Rodler, Sales Manager Custom Synthesis, Bachem

Susanne Rodler is Sales Manager Custom Synthesis at Bachem AG. Prior to Bachem, Susanne Rodler worked for a big pharmaceutical company, where she was involved in clinical studies for cancer treatment. Susanne Rodler is a chemist by training and received her PhD for her work on the synthesis of organic dyes.

Message Presenter

Dr. Stefanie Dobitz, Sales Manager Custom Synthesis, Bachem

Stefanie Dobitz is Sales Manager Custom Synthesis at Bachem AG. Before joining Bachem, Stefanie Dobitz earned her doctoral degree from ETH Zurich where she worked on the synthesis and biological evaluation of oligoproline-based peptides for tumor targeting. Previously, she studied chemistry at the Justus Liebig University Giessen, receiving her B.Sc. and M.Sc. for her work on stereoselective oxidations using peptide-based organocatalysts.

Message Presenter

Dr. Erik Schrader, Marketing Specialist, Bachem

Erik Schrader is Marketing Specialist at Bachem AG. Before joining Bachem, Erik Schrader earned his doctoral degree in chemistry from ETH Zurich where he worked on the synthesis and application of acylphosphines. Before his doctoral studies, he worked for half a year at a big chemical company on the synthesis of additives for performance materials.

Message Presenter

Who Should Attend?

Scientists in Pharma, Biotech, Universities and Hospitals including:

  • Research Scientists and Associates
  • PostDocs and PhDs
  • Scientific Advisors
  • Directors of Research and Development
  • In vivo imaging, flow cytometry and microscopy labs

Other Professionals in the Life Sciences including:

  • Product Managers
  • Marketing Managers
  • Diagnostics Professionals

What You Will Learn

  • New developments in dye labeling
  • An overview of known dye labels
  • How to design the right substrate for your application
  • An overview of synthetic methods and pitfalls and more

Xtalks Partner

Bachem

Bachem provides an efficient and high quality custom synthesis service for peptides and amino acids. In our certified production sites (GMP or ISO 13485), we are capable of synthesizing peptides in mg to kg-scale and offer a large selection of peptide modifications and labeling.

Bachem is a listed technology-based company focused on peptide chemistry. The company provides a full range of services to the pharma and biotech industries. It specializes in the development of innovative, efficient manufacturing processes and the reliable production of peptide-based active pharmaceutical ingredients. A comprehensive catalog of biochemicals and exclusive custom syntheses for research labs complete the service portfolio. Headquartered in Switzerland with subsidiaries in Europe and the US, the group has a global reach with more experience and know-how than any other company in the industry. Towards its customers, Bachem shows total commitment to quality, innovation and partnership.

Bachem. Pioneering Partner for Peptides.

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