Rethinking Lupus: The Emerging Role of T Cells in SLE Pathophysiology and Diagnostics

Life Sciences, Pharma, Healthcare,
  • Monday, March 10, 2025 | 1pm EST (12pm CST / 10am PST)
  • 60 min

Discover an informative webinar in which the expert speakers discuss the role of T Cells in the diagnosis of systemic lupus erythematosus (SLE).

This webinar examines 30 years of research on anti-lymphocyte antibodies specific to lupus, their impact on cytokine profiles and immune dysregulation within the context of SLE. This webinar will include cutting-edge advancements in semi-quantitative flow cytometry assays for T Cell biomarkers, including TC4d and T Cell autoantibodies, as well as findings from a multi-centered clinical validation study demonstrating their diagnostic accuracy.

This webinar bridges historical insights with modern innovations, providing a comprehensive perspective on SLE pathogenesis and diagnostic advancements.

Register for this webinar today to understand the critical role of T Cells in diagnosing SLE pathophysiology.

Speakers

Dr. Brittany Partain, Exagen Inc.

Dr. Brittany Partain, PhD, Senior Medical Science Liaison, Exagen Inc.

A biomedical engineer with more than seven years of cross-discipline research, Dr. Brittany Partain serves as Senior Medical Science Liaison at Exagen Inc., a leading provider of autoimmune testing solutions. In her role, Dr. Partain leverages her scientific and medical expertise to help Exagen achieve its goals, equipping providers with advanced testing for accurate and timely diagnosis, prognosis and monitoring of autoimmune conditions, as well as improving patient outcomes.

Dr. Partain received her PhD in biomedical engineering from the University of Florida, with a thesis focused on understanding the pathophysiology of osteoarthritis and mitigating inflammation in osteoarthritis.

Message Presenter
Dr. Vasileios Kyttaris, Israel Deaconess Medical Center

Dr. Vasileios Kyttaris, MD, PhD, FACR, Internist and Rheumatologist, Boston, MA

Dr. Vasileios Kyttaris is an Assistant Professor of Medicine at Harvard Medical School and an attending rheumatologist at Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts. He received his medical degree in 1994 from the University of Patras, Greece. He completed his residency training in Internal Medicine at the Washington Hospital Center in 2001.

He subsequently completed fellowships in rheumatology and autoimmune diseases in 2003 and 2004 at Washington Hospital Center and Walter Reed Army Institute of Research. Dr. Kyttaris is the author or co-author of more than 100 papers on lupus. He was the Principal Investigator on two studies funded by the National Institutes of Health, NFAT/AP-1 cooperation in SLE T Cells, and The Role of Interleukin 23 in Lupus.

Dr. Kyttaris is the 2016 recipient of the Mary Betty Stevens Young Investigator Prize awarded by the Lupus Foundation of America. He currently heads the Lupus Center of Excellence at BIDMC and conducts clinical and translational research in SLE.

Message Presenter

Who Should Attend?

This webinar will appeal to:

  • Rheumatologists/Rheumatology Nurse Practitioners/Rheumatology Physician Assistants
  • Generalists
  • Immunologists
  • Healthcare professionals
  • Clinical researchers at hospitals and specialist consultants in rheumatology and clinical immunology
  • Program leads/Heads of Rheumatology at pharma and biotech companies

What You Will Learn

Attendees will gain insights into:

  • Evolution of understanding SLE as a disease predominantly driven by B Cells and Type I interferon to the growing recognition of the crucial role that T Cells play
  • Advancements in biomarker detection with the development of novel, semi-quantitative flow cytometry assays to detect T Cell-bound complement activation (TC4d) and T Cell autoantibodies (TIgG and TIgM)
  • Clinical validation of T Cell markers from a multi-centered clinical validation study demonstrating their diagnostic utility in distinguishing lupus from other autoimmune diseases and healthy controls
  • How T Cell learnings are reshaping the understanding of lupus pathogenesis and paving the way for innovative diagnostic tools

Xtalks Partner

Exagen Inc

Exagen Inc. is a patient-focused and discovery-driven commercial-stage life sciences company. We aid patients and healthcare providers in the diagnosis, prognosis, and management of autoimmune conditions. Our relentless pursuit for laboratory excellence has enabled us to develop next-generation autoimmune testing to help empower physicians and improve patients’ lives.

You Must Login To Register for this Free Webinar

Already have an account? LOGIN HERE. If you don’t have an account you need to create a free account.

Create Account