Grammy-winning artist Lil Jon has joined forces with Exact Sciences in a dynamic campaign to boost awareness about colon cancer screening. Dubbed “Get Low #2,” the initiative reimagines his iconic early 2000s hit to drive a critical message: encouraging the approximately 60 million Americans overdue for colon cancer screening to prioritize their health.
By blending music and health advocacy, the campaign underscores the importance of early detection while spotlighting the non-invasive Cologuard test.
Colon cancer is the second leading cause of cancer-related deaths in the US, but it is highly treatable when caught early. Many patients, however, hesitate to undergo colonoscopy due to fears of pain, embarrassment or concerns about the procedure’s invasiveness.
The Cologuard test offers a simple, at-home alternative, detecting DNA markers and blood in stool linked to colorectal cancer and precancer.
In a quirky and memorable moment from the campaign, Lil Jon jams alongside a golden commode to sing out the prep and collection process for the test kit: receive a kit by mail, collect a stool sample using the provided materials and send it back via prepaid shipping.
Designed for adults aged 45 and older at average risk, the test eliminates invasive preparation and allows individuals to complete the process in the privacy of their homes.
Lil Jon’s involvement is about more than a remix; it’s a call to action. His reach and vibrant personality aim to break cultural and societal barriers, particularly in underserved communities where screening rates are lower and mortality risks are higher. By making an often-uncomfortable topic more relatable, the partnership hopes to encourage people to take proactive steps toward their health.
Exact Sciences, known for its innovative cancer diagnostic tools, views this collaboration as part of its broader mission to advance colorectal cancer prevention. Future efforts will include expanding community outreach and leveraging strategic partnerships to drive awareness and early detection initiatives.
Related: Exact Sciences and Katie Couric Partner for Colon Cancer Awareness Month with Cologuard TV Ad
Building on a tradition of engaging influential voices, Exact Sciences continues its mission to reduce the burden of colorectal cancer. In 2022, journalist and cancer advocate Katie Couric led the “Mission to Screen” campaign, sharing her personal story to inspire early detection. That same year, actors Ryan Reynolds and Rob McElhenney partnered with the Colorectal Cancer Alliance for the “Lead From Behind” initiative, using humor and transparency to demystify colonoscopies.
More recently, Exact Sciences collaborated with actor and philanthropist Carlos Ponce to address low screening rates among Hispanic adults, where less than half of eligible individuals are screened. This campaign focused on culturally tailored education, using Spanish-language resources to break stigmas and promote early detection.
With “Get Low #2,” Exact Sciences continues to demonstrate how authentic, relatable storytelling and accessible solutions like the Cologuard test can lower barriers to screening, empowering more people to take proactive steps toward prevention.
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