An Overview of the Severe Asthma Questionnaire (SAQ) – An Assessment of Quality of Life

Life Sciences, Clinical Trials, Healthcare,
  • Thursday, December 12, 2019

Questionnaires designed to measure the quality of life in individuals with mild and moderate asthma cannot be applied to individuals with severe asthma. This has led to the development of the Severe Asthma Questionnaire (SAQ), a new patient-reported outcome (PRO). The SAQ was developed according to the US Food and Drug Administration (FDA) PRO guidelines that require patient input. Patients were treated as partners in the process of questionnaire construction rather than only as a source of information. The questionnaire takes into account not only the impact of asthma symptoms but also the effects of treatment on Health-Related Quality of Life (HRQoL). The questionnaire produces two scores: the SAQ score is the aggregation of 16 different QoL domains and the SAQ-global score is the figure given on a 100-point scale. The scale takes between 3 to 6 minutes to complete, but completion time reduces on subsequent occasions.

Evidence demonstrates its superior cross-sectional sensitivity and its design makes it a sensitive tool to measure response in severe asthma clinical trials. The SAQ can be used in clinical practice to gain insights into living with severe asthma from the patient’s perspective. Currently, it’s being added to international patient registries.

Join this free webinar to learn how and why the SAQ was developed and how it’s being applied in clinical practice.


Dr. Matthew Masoli, MBBS, MRCP, MD, Respiratory Consultant, Royal Devon and Exeter Hospital NHS Trust

Dr. Matthew Masoli is a respiratory consultant and honorary senior clinical lecturer at the Royal Devon and Exeter Hospital NHS Trust. He has a particular interest in patients with severe and difficult-to-control asthma and leads the severe asthma service. His current research interests include investigating the quality of life impairment of the disease and its treatment in severe asthma. He has published widely in the field and has been involved in a number of national asthma guideline committees.

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Prof Michael Hyland, PhD, FBPS, CPsychol, Honorary Professor, University of Plymouth & Professor of Psychology, Plymouth Marjons University

Professor Michael Hyland is an honorary professor of the University of Plymouth and professor of psychology at Plymouth Marjons University. He was the first respiratory psychologist in the UK and has published on quality of life assessment and management of asthma since 1991. His current interests are the wider impacts of severe asthma and how best to manage patients from a holistic perspective.

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Marie Dulac, Author Relations Specialist, Mapi Research Trust

Marie Dulac is an Author Relations Specialist who manages health research questionnaire distribution and licensing for Mapi Research Trust.

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Who Should Attend?

This webinar will appeal to the following individuals:

  • Healthcare professionals interested in severe asthma
  • Clinical researchers
  • Pharmaceutical company personnel involved in severe asthma
  • People living with severe asthma

What You Will Learn

Attendees will learn: 

  • Why questionnaires designed to measure quality of life in mild and moderate asthma are not valid when used for severe asthma
  • How the SAQ was developed using input from patients as recommended by FDA PRO guidelines
  • SAQ content and the different types of problems that patients with severe asthma have
  • How to use the SAQ in clinical practice and in clinical trials
  • An overview of new and ongoing research using the SAQ

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