Biofermentation Success Through pH and DO Management

Biotech, Life Science, Pharma, Pharma Manufacturing & Supply Chain,
  • Thursday, August 14, 2025 | 1pm EDT (12pm CDT / 10am PDT)
  • 60 min

Biofermentation is a fundamental element of pharmaceutical manufacturing, enabling the production of essential biologics, including antibiotics, vaccines, therapeutic proteins and enzymes. Accurate control of pH and dissolved oxygen (DO) is vital for maximizing cell viability, product yield and process reproducibility. These factors directly influence microbial metabolism, protein expression and overall bioprocess efficiency.

This webinar examines the key role of advanced pH and DO sensing technologies in enhancing fermentation for pharmaceutical applications. Emphasis will be placed on sensor accuracy, real-time data integration and the use of feedback control systems to maintain optimal culture conditions throughout the production cycle.

Case studies will demonstrate how improved sensor performance can lower batch failures, enhance scalability and support compliance with regulatory standards such as cGMP and FDA guidelines. Attendees will gain practical insights into how modern sensor systems — integrated with data analytics and process automation — can significantly enhance the performance and reliability of biofermentation in pharmaceutical manufacturing.

Join the featured speakers to:

  • Explore practical approaches to implementing pH and DO monitoring in pharmaceutical fermentation
  • Gain insights from real-world case studies on minimizing batch failure and improving yield
  • Learn how experts align bioprocess control with regulatory expectations and manufacturing goals

Register to learn how advanced pH and DO control can optimize biofermentation processes, improve product yield and support regulatory compliance in pharmaceutical manufacturing.

Speaker

Eric Robbibaro, M4 Knick

Eric Robbibaro, Life Sciences Industry Manager, M4 Knick

Eric Robbibaro is an automation specialist with years of experience working with industrial and life science manufacturing systems. As the Life Sciences Industry Manager for M4 Knick, he leverages accrued knowledge to recommend innovative digital and automated measurement solutions to the pharmaceutical industry.

As an Electrical Engineer with experience in Technical Sales, Eric focuses on providing the most efficient solutions possible for critical liquid analytics processes. Eric serves as a committee member for SLAS, is an active member of ISPE and served as an executive committee member for LRIG for four years. His passion for the life sciences industry and technical background make him a valuable resource for advancing process measurement and automation in the pharmaceuticals sector.

Message Presenter

Who Should Attend?

This webinar will appeal to small to large pharma and biopharma manufacturers in Canada and the US, particularly those in roles such as:

  • Quality Control (QC) Analyst/Quality Assurance (QA) Specialist
  • Maintenance Technician/Manufacturing Technician
  • Validation Engineer/Process Engineer/Analytical Chemist
  • Bioprocess Technician/Instrumentation Technician/Laboratory Technician
  • Technical Support Specialist/Pharmaceutical Scientist
  • Production Supervisor/Process Development Scientist/GMP Compliance Specialist
  • Environmental Monitoring Technician

What You Will Learn

Attendees will gain insight into:

  • The critical role of pH and dissolved oxygen (DO) control in pharmaceutical biofermentation
  • How advanced sensor technologies improve accuracy, responsiveness and reliability in bioprocess monitoring
  • Strategies for real-time data integration and feedback control to maintain optimal culture conditions
  • The impact of improved monitoring on product yield, consistency and regulatory compliance

Xtalks Partner

M4 Knick

Since 2013, M4 Knick has been dedicated to simplifying process analytics for manufacturers, OEMs, and municipalities. Headquartered in Cincinnati, OH, the company focuses on providing reliable and efficient solutions for liquid analytical measurements, including pH, ORP, conductivity, and oxygen sensors.

M4 Knick’s key technology includes Memosens smart sensors, which offer real-time sensor health data, reduce calibration times by up to 80%, and significantly extend sensor life. These innovations help customers eliminate measurement drift and interference, ensuring consistent and reliable results.

Through a partnership with Knick Elektronische Messgeräte in Berlin, Germany, M4 Knick is committed to delivering high-quality, dependable service. The team works closely with clients to understand their specific application needs and provide tailored solutions that maximize uptime and efficiency.

M4 Knick aims to lead the future of process analytics by continually evolving its product offerings and enhancing customer experiences. The company’s goal is to make liquid analysis as convenient and reliable as possible, ensuring customers can focus on their core operations.

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