Demystifying the Microbiome: Connecting Metabolomics to Health and Drug Response

Life Sciences, Pharmaceutical, Drug Discovery & Development, Drug Safety, Biomarkers,
  • Wednesday, November 10, 2021

Interest in the role of the human microbiome in health and disease is exploding.

The gut microbiome describes the full array of microorganisms that live in the gut. Most of these microbes supply crucial ecosystem services that benefit the entire host-microbe system. However, studies have shown that disruption of the gut microbiome, either through loss of beneficial functions or the introduction of maladaptive functions by invading microbes, can contribute to disease.

While the collection of microbial genomes, or the metagenome, can provide information relating to the diversity of these microbes, it is not sufficient to detail the function of the microbiome. The unique capability of metabolomics to measure microbiome-derived metabolites sheds light on the biological activity of bacterial communities in ways that other omics technologies cannot.

In this webinar you will learn more about:

  1. How a functional metabolomics readout of the microbiome can complement other omics approaches to provide a deeper understanding of host-microbiome interactions and how these are impacted by disease and novel therapeutics
  2. How the incorporation of metabolomics into drug discovery and development programs can assist in understanding the mechanism of action, safety, and efficacy of novel treatments
  3. Metabolon’s new microbiome solutions, including the metabolites SmartPanel™ andGood Clinical Practice (GCP)-validated assays, that can provide actionable insights to advance drug development

Join Metabolon experts as they discuss new tools to demystify the microbiome and the complex interactions that modulate human health and drug response.

Speaker

Brian Keppler, Ph.D.

Brian Keppler, Ph.D., Director of Discovery and Translational Sciences at Metabolon

As Director of Discovery and Translational Sciences at Metabolon, Inc., Dr. Brian Keppler has worked with Metabolon’s global Pharmaceutical, Biotechnology and Applied Markets clients since 2011. He received his doctorate from the University of North Carolina at Chapel Hill and completed postdoctoral training in the National Institute of Environmental Health Sciences’ (NIEHS) Laboratory of Molecular Carcinogenesis.

Message Presenter

Who Should Attend?

This webinar will benefit professionals working in drug discovery and development, with relevant job titles including:

  • Translational Medicine Managers
  • Biomarker Study Operations Managers
  • Heads of R&D
  • R&D Managers
  • Science Directors/Translational Scientists
  • Business/Science Buyers
  • Analytical Chemists
  • Research Scientists
  • Lab Managers
  • Other Bench Users

What You Will Learn

In this webinar you will learn more about:

  1. How a functional metabolomics readout of the microbiome can complement other omics approaches
  2. How the incorporation of metabolomics into drug discovery and development programs can assist in studying novel treatments
  3. Metabolon’s new microbiome solutions, including the metabolites SmartPanel™ and Good Clinical Practice (GCP)-validated assays

Xtalks Partner

Metabolon

Metabolon deciphers thousands of discrete chemical signals from genetic and non-genetic factors to reveal biological pathways. We make connections where other ‘omics cannot, and provide the definitive representation of the phenotype.

Our work measures inputs from internal and external factors such as health, disease, nutrition, microbiome, medication, pollution, and more, to drive success in answering scientific questions about health and disease.

Every day, we accelerate research that leads to successes in biopharma, population health, consumer products, agriculture, wellness, and academic and government research sectors. This work has enabled modern science to gain a foothold in our understanding of complex disease, ultimately leading to the creation of new treatments that impact individuals and communities globally. Our scalable, customizable metabolomics solutions provide support across the research continuum from discovery through clinical trials, to in-market life cycle management.

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