Many RNA programs are under increasing pressure to compress development timelines while ensuring consistent, fit-for-purpose RNA quality and delivery readiness for downstream applications. This webinar will highlight how an integrated in vitro transcribed (IVT) RNA workflow can accelerate progression from gene to mRNA, including rapid options for time-sensitive projects, without compromising robust quality control and process design.
The session will explore support for multiple RNA modalities—linear mRNA, circular RNA (circRNA) and self-amplifying RNA (saRNA)—and discuss why modality-specific design, manufacturing and quality strategies are essential to optimize expression, stability and durability across platforms.
Participants will also discover how coordinated RNA and lipid nanoparticle (LNP) development enables faster candidate selection, minimizes experimental iteration and helps de-risk early development on the path toward clinical advancement.
Register to learn how integrated IVT RNA and RNA-LNP workflows can help move RNA discovery programs from construct design to actionable data with greater speed and confidence.
Speaker
Shambhavi Shubham, PhD, Senior Manager R&D, GenScript
Dr. Shambhavi Shubham has over a decade of experience in nucleic acid biochemistry and RNA platform development and is currently a Senior Manager of R&D at GenScript Biotech’s Innovation Center. In her role, she leads innovation initiatives focused on advancing linear, circular and self-amplifying RNA systems for gene editing and other therapeutic applications, including vaccines, protein replacement therapies and cell therapy.
At GenScript, she drives mRNA engineering strategies that improve translation efficiency, stability and manufacturability. She has authored several peer-reviewed publications and co-invented multiple patents related to RNA design, manufacturing and delivery technologies. Her expertise includes RNA chemistry optimization, process development and accelerating discovery-to-clinic workflows for advanced RNA therapeutics.
Message PresenterWho Should Attend?
This webinar will appeal to:
- Scientists and R&D leads working on mRNA-based therapeutics
- Molecular Biology Researchers focused on IVT mRNA production
- RNA Therapeutics teams exploring scale-up and IND readiness
- Biotech professionals in vaccine, gene & cell therapy development
What You Will Learn
Attendees will gain insights into:
- Accelerated synthesis for discovery research
- Parallel screening of RNA constructs and LNP formulations
- Optimized expression and stability across linear mRNA, circRNA and saRNA
- How integrated RNA-LNP workflows shorten the path from discovery to clinic
Xtalks Partner
GenScript
GenScript is the leading contract research organization in the world providing gene, peptide, protein, CRISPR, and antibody. Since its foundation in 2002, GenScript has grown exponentially through partnerships with scientists conducting fundamental life science research, translational biomedical research, and early stage pharmaceutical development. The company is recognized as having built a best-in-class capacity and capability for biological research services, encompassing gene synthesis, peptide synthesis, custom antibody and protein engineering, and in vitro and in vivo pharmacology – all with the goal to make people and nature healthier through biotechnology by scripting possibilities.
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