Immuno-Oncology: Functional Assays for Immune Checkpoint Inhibitors as Emerging Therapeutics

In the immuno-oncology space, the regulation of the immune system is paramount in the development of a successful therapeutic. This webinar will showcase assays to evaluate cellular pathways of immune cells, T-cells, and macrophages while highlighting functional and immunogenicity assays developed in support of current and emerging therapeutics. The speakers, Sofie Pattijn, an immuno-oncology expert who leads the ImmunXperts team in Belgium, and Thibaut Janss, one of their leading expert scientists for immuno-oncology, will outline how in vitro methods mimic the tumor environment to measure therapeutic functionality.

Register for this webinar to hear the speakers highlight how in vitro models are essential at critical phases of development to support lead candidate selection or generate data for evaluation in an exploratory clinical phase. As the development transitions through pre-IND to clinical phases, there are a variety of cellular assays and clinical applications that support the drug development process.

Speakers

Sofie Pattijn, CTO and Co-Founder, ImmunXperts, a Nexelis Company

Sofie Pattijn, Chief Technology Officer and Founder of ImmunXperts, has over 20 years of experience in the field of immunogenicity assessment (vaccines and biotherapeutics) and in vitro assay development with a focus on functional assays for immunogenicity, immuno-oncology, and cell and gene therapy products. She has extensive hands-on lab experience and has managed and coached several in vitro teams over the last decade. From 2008 to 2013, Sofie was head of the in vitro immunogenicity group at AlgoNomics (Ghent, Belgium) and Lonza Applied Protein Services (Cambridge, UK). Prior to that, she worked at Innogenetics in Belgium for over 15 years.

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Thibaut Janss, Lead Scientist, ImmunXperts, a Nexelis Company

Thibaut Janss holds a Master’s degree in Biochemistry, Molecular and Cellular Biology from the University of Liège. He received his PhD (2012-2016) at the GIGA Research Center in Liège, where he acquired extensive experience in the immunology field, working on dendritic cells and T cells interactions. During this period, he also developed an in-depth knowledge of flow cytometry. He joined ImmunXperts at the beginning of 2017 and is currently leading the immuno-oncology team.

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