This webinar will provide a short introduction to immuno-oncology, the shortcomings of current standard of care, checkpoint inhibitors and the mechanism of action of oncolytic virotherapies. The featured speaker will discuss selective replication of the oncolytic virus VSV-GP in tumor cells, tumor cell lysis and reshaping of the tumor microenvironment. The results from this study will explore the potential of VSV-GP as an immuno-oncology enabler for a broad range of cancers in poorly “T-cell inflamed” tumors and highlight VSV-GP as a non-mutagenic virus that synergizes with other immunotherapies as well as targeted therapies.
Philipp Müller, PhD, Senior Principal Scientist, Cancer Immunology & Immune Modulation Department, Boehringer Ingelheim
Dr. Philipp Müller received his PhD in Biochemistry from the University of Basel in 2009 (Biozentrum, Prof. Jean Pieters), with a major focus on the immunology of infectious diseases, immune cell signalling and in vivo models of immune cell function as well as development. Over the last 10 years, his research has been dedicated to cancer immunology and immunotherapy. He has worked on and published in high ranking journals on the immune-promoting properties of antibody-drug-conjugates, bispecific antibody formats as well as agonistic antibodies, such as anti-CD40, and their therapeutic combination with immune-checkpoint blockade. Dr. Philipp Müller is currently leading a research/project team as a senior principal scientist within the cancer immunology & immune modulation department of Boehringer Ingelheim (Biberach an der Riß, Germany) with a major focus on next-generation oncolytic viruses and novel immuno-oncology concepts.
Who Should Attend?
This webinar will appeal to individuals with the following or related job titles:
- Research Scientists
- Clinical Researchers
- Medical Researchers
- Industry Scientists
- Lab Directors/PI
- Post Doc Students
- Grad Students
Working in the following research areas:
- Immune checkpoints
- Cancer immunology
- Biomarker discovery
- Companion diagnostics
- Molecular pathology
- Precision medicine
What You Will Learn
Attendees will learn about:
- Introduction to immuno-oncology
- Shortcomings of current standard of care
- Checkpoint inhibitors
- Mechanism of action of oncolytic virotherapy, e.g. VSV-GP
- Application of VSV-GP in different cancers
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