Osmolality as a Key to Diagnosing Diabetes Insipidus

The diagnosis of diabetes insipidus (DI) hinges on the careful assessment of the body’s ability to concentrate urine in response to water deprivation. Among the array of diagnostic tools available, osmolality testing plays a pivotal role in distinguishing central and nephrogenic DI from primary polydipsia and other causes of polyuria.

By systematically monitoring changes in serum and urine osmolality during the water deprivation test, clinicians can precisely evaluate renal concentrating capacity and antidiuretic hormone (ADH) responsiveness. This process not only enhances diagnostic specificity but also informs subsequent therapeutic strategies, ultimately leading to improved patient outcomes. The incorporation of osmolality measurements into water deprivation protocols ensures a robust, safe, evidence-based approach for the nuanced diagnosis of DI.

This webinar will guide attendees through the structured application of osmolality data during each phase of the water deprivation test. It will cover how clinicians interpret serum and urine values to determine when testing should proceed or stop, how urine concentration patterns inform diagnosis and how response to desmopressin provides critical clues for distinguishing underlying etiologies.

Register for this webinar to learn how osmolality testing supports the diagnosis and management of DI.

Speaker

Dr. Arian Gower, MD, Nephrologist, Renal Consultants Medical Group

Dr. Arian Gower’s academic path took him from Wheaton College in Norton, Massachusetts, where he completed his undergraduate degree, to Rosalind Franklin University in Chicago for his medical school training and Master’s degree in Healthcare Administration and Management. His residency brought him to MountainView Hospital, part of the Sunrise Consortium in Las Vegas, where he had the privilege of serving as Chief Resident.

Following his residency, he pursued a nephrology fellowship at the University of Colorado and moved to Los Angeles in 2021 to become a full-time Nephrologist with Renal Consultants Medical Group, one of the longest-established practices in the San Fernando and Santa Clarita valleys.

In addition to his clinical work, he is passionate about teaching and is proud to serve as the Associate Program Director of an internal medicine residency program, where he mentors and guides the next generation of physicians.

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