What if the knowledge to answer questions about the tissue microenvironment was all in one place? The cellular landscape requires a combination of competencies to effectively extract data that has therapeutic value. The appropriate biomarkers should be defined and a robust assay should be built to ensure that the imaged tissue can be thoroughly assessed and understood. Spatial phenomics encompasses the entire workflow required to find significant spatial patterns in tissues.
The workflow for spatial phenomics includes assay development, image analysis, spatial biology, data mining and validation of the findings. The journey through the entire immuno-oncology development pipeline can be supported. This involves defining and framing a specific scientific question and developing a panel, all the way to delivering data-driven answers that enable a project to move forward. By combining scientific expertise with proven assays and leading-edge technologies, the efficiency and accuracy can be increased for multiplex projects.
Join this webinar to see practical examples that introduce the power of spatial analysis to drive towards meaningful answers about the most promising target readouts, immunological response to therapy, or expression profiles across multiple indications. Attendees will learn about how a robust assay allows the move from early feasibility and proof of concept to more widely applicable use with larger study sizes. In addition, the co-development of biomarker panels and robust analysis algorithms enable de-plexing. This allows the use of robustly trained algorithms to distinguish cell populations on low plex or even hematoxylin and eosin (H&E)-stained tissues.
Speaker
Dr. Florian Leiss, VP, Digital Health Strategies, Ultivue
Florian Leiss is the Vice President of Ultivue’s Digital Health Strategies business. He has previously covered roles in business development, corporate strategy, product management and marketing, and marketing communications. He studied Biochemistry (Technical University Munich) and holds PhDs in Neuroscience (Max Planck Institute for Neuroscience, Munich) and Philosophy (Ludwigs-Maximilians-University, Munich).
Message PresenterWho Should Attend?
This webinar will be of particular interest to scientists, PhDs and post-docs in immuno-oncology research and computational pathology, translational scientists and bioassay experts.
What You Will Learn
- Discover the power of spatial phenomics to increase the resolution of the biological landscape of immuno-oncology
- Find out how an integrated approach to defining assay development leads to actionable and robust data
- Learn how an agile approach to image analysis can lower traditional barriers to adoption of digital solutions for drug development pipelines
Xtalks Partner
Ultivue, Inc.
Ultivue, Inc. provides researchers and scientists with multiplex biomarker assays for tissue phenotyping and digital pathology. Its proprietary InSituPlex® technology enables advanced exploration and interrogation of tissue samples for precision medicine research. These highly customizable solutions and scientific consultative approach strengthen and accelerate biomarker discovery and drug development programs. For more information, visit ultivue.com
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