Running Successful Neuropathology Studies: Sampling and Preparing Nervous System Tissues for Microscopic Evaluation

Life Sciences, Laboratory Technology, Fundamental Research,
  • Friday, June 07, 2024

Discover an informative webinar that will provide a comprehensive overview of techniques and strategies essential for effective neuropathology evaluations and toxicity studies.

In this webinar, the speaker will introduce various fixation, processing and staining techniques that are essential for visualizing morphologic changes in the central and peripheral nervous systems. Attendees will also receive tips on planning and preparing for quantitative neuropathologic techniques such as stereology and nerve histomorphometry.

The expert speaker will also share invaluable recommendations and best practices for the collection and preparation of nervous system tissues. This webinar will also discuss various staining techniques, their benefits and how they are used for the central and peripheral nervous systems.

Attendees will also gain insights on how to plan ahead for using quantitative neuropathologic techniques in studies. Lastly, attendees will learn how they can achieve optimal sampling and evaluation strategies for good laboratory practices (GLP) and non-GLP neuropathology studies.

Register for this webinar today to learn how neuropathology studies should be conducted and gain practical tips on preparing for advanced quantitative neuropathologic techniques.


Dr. Lisa Mangus, StageBio

Dr. Lisa Mangus, DVM, PhD, DACVP, Senior Pathologist, StageBio

Dr. Lisa Mangus is a veterinary anatomic pathologist with experience conducting neuropathologic investigations in both industrial and academic research settings. Since joining the StageBio team in 2021, Dr. Mangus has evaluated numerous studies that employ a broad range of specialized tissue processing, staining and molecular techniques to thoroughly characterize the effects of test articles, including novel gene and cell therapies, on the central and peripheral nervous systems.

Prior to joining StageBio, Dr. Mangus was a faculty member at the Johns Hopkins University School of Medicine, where she also completed her PhD with a focus on neurovirology and neuroimmunology. Concurrent with her PhD training, Dr. Mangus completed a residency in comparative anatomic pathology at Johns Hopkins and joined the American College of Veterinary Pathologists in 2014.

Dr. Mangus earned her DVM from the Ohio State University College of Veterinary Medicine, followed by a clinical internship in small animal medicine and surgery at Veterinary Referral Associates in Gaithersburg, MD. In addition to neuropathology, she brings a special interest and experience in the pathology of zoo and aquatic species.

Message Presenter

Who Should Attend?

This webinar will appeal to:

  • Study Directors
  • Toxicologists
  • Pathologists
  • Consultants

What You Will Learn

Attendees will gain insights into:

  • Recommendations and best practices for collecting and preparing nervous system tissues during expanded and dedicated neuropathology evaluations, as well as general toxicity studies
  • Various fixation, processing and staining techniques used to visualize morphologic changes in the central and peripheral nervous systems
  • How to plan and prepare in advance for quantitative neuropathologic techniques such as stereology and nerve histomorphometry
  • Optimal sampling and evaluation strategies for good laboratory practices (GLP) and non-GLP neuropathology studies

Xtalks Partner


StageBio is a leading provider of GLP-compliant necropsy, histology, pathology and specimen archiving services for the biopharmaceutical, medical device, academic, government and contract research industries. The company operates four GLP laboratories as well as two GLP specimen archiving facilities in the U.S. and Europe, with substantial continued investment in facility and technology infrastructure to meet the growing demand for high-quality histopathology services globally. StageBio has a team of 30 board-certified veterinary pathologists and more than 100 laboratory personnel on staff supporting our unified commitment to quality, scientific integrity and client satisfaction. Learn more at

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