Spatial transcriptomics is a powerful technique for quantitation of gene expression within histopathology samples, such as heterogeneous areas of tumors, their adjacent microenvironment or related inflammatory/immune cells. The team at Cellecta uses the Nanostring GeoMx Digital Spatial Profiling (DSP) platform to provide simultaneous, highly multiplex spatial profiling of proteins or RNA in formalin-fixed paraffin-embedded (FFPE) tissues.
In this webinar, featured speakers will first review how the methodology works, and then use specific case studies to illustrate key considerations in experimental design, data collection and interpretation. The webinar will also highlight important benefits of spatial profiling services. This includes expert pathologist consultation regarding sample preparation, as well as optimal selection of regions of interest (ROIs) to best address investigators’ questions.
Register for this webinar to learn how best to apply spatial transcriptomics techniques in gene expression studies.
Lester Kobzik, MD, Chief Medical Officer, Cellecta, Inc.
Dr. Lester Kobzik is an experimental pathologist with expertise in lung disease. He is Professor of Pathology (Emeritus) at Harvard Medical School and currently serves as Chief Medical Officer at Cellecta, Inc in Mountain View, CA, where he also directs the spatial transcriptomics service.
Paul Diehl, PhD, Chief Operating Officer, Cellecta, Inc.
Dr. Paul Diehl joined Cellecta, Inc. in July 2010 where he applies over two decades of experience in biotechnology to developing and expanding the company’s commercial and collaborative activities. Prior to joining Cellecta, Dr. Diehl held various marketing and business development positions at B-Bridge International, Agilent Technologies, Clontech Laboratories and other companies. Dr. Diehl received his BA in Biology from LaSalle University in Philadelphia, PA and his PhD in Biochemistry from Washington State University in Pullman, WA.
Who Should Attend?
This webinar will benefit professionals working in pharma, biotech, government and academic medical centers, with relevant job titles including:
- Research Scientists, Associates, Assistants
- Senior or Principal Researchers
- Senior or Principal Investigators
- Senior or Principal Scientists
- Drug Discovery and Validation Scientists
- Preclinical Scientists
- Directors of R&D
What You Will Learn
- Overview of spatial transcriptomic profiling using the Nanostring GeoMx platform
- Key points in experimental design and data analysis
- Strengths and limitations of the methodology
- Benefits offered by spatial transcriptomic profiling services
Cellecta is a trusted provider of functional genomic products and services with over 15 years’ experience working with the world’s leading pharma, biotech and academic institutions. Our portfolio includes products and services for loss-of-function and gain-of-function phenotypic screening, cell barcoding and gene expression profiling. This includes design and manufacture of custom and genome-wide CRISPR and RNAi libraries, lentiviral constructs and cell engineering services. We also offer expression profiling assays and spatial transcriptomic services for drug target and biomarker discovery and other applications.