Traditionally, peptide purification has relied on preparative high-performance liquid chromatography (prep-HPLC), known for its excellent resolution and impurity removal. However, this method is often hampered by low column loading capacity and extended purification times, which makes it inefficient and difficult to scale. In response to these challenges, sustainable flash chromatography can be an alternative to prep-HPLC.
Automated reversed-phase flash purification offers a fast, flexible and cost-effective alternative to traditional methods, enabling researchers to purify synthetic peptides efficiently and redirect their efforts toward more important tasks. This approach addresses issues such as molecule-specific optimization, scale-up difficulties and the inefficiencies of current processes, providing a greener and more efficient solution.
As the demand for greener practices in chemistry labs grows, efforts to reduce waste generation and increase the use of safer solvents have become critical for organizations and research groups synthesizing and purifying peptides. Suboptimal purification techniques significantly increase solvent consumption and lead to duplicated efforts when initial purifications fail. Furthermore, solvents commonly used in peptide purification are now under scrutiny, leading to increasing use restrictions and the need for safer, more sustainable alternatives.
In this webinar, the expert speakers will explore how innovative purification strategies can help advance green initiatives. They will present strategies behind sustainable flash purification of peptides, focusing on how they reduce solvent consumption, minimize purification time while maximizing final purity. Additionally, they will discuss how this technology can help meet the evolving needs of peptide synthesis and purification while supporting a more environmentally conscious approach to laboratory practices.
Register for this webinar today to discover how sustainable flash purification is transforming peptide purification.
Speaker
Austin Schlirf, Application Scientist, Biotage®
Austin Schlirf has a background in Biomedical Engineering where he researched a variety of biomaterial applications from synthetic bioinspired hydrogels to mucin glycopeptide mimetics.
Austin serves as an Application Scientist at Biotage® where his role supports the North American system installed base for peptide and small molecule research. This includes Biotage® tools supporting synthesis, purification and dry down of samples primarily at laboratory scale.
Message PresenterWho Should Attend?
This webinar will appeal to:
- Graduate students
- Post-doctoral fellows
- Research Associates/Research Scientists
- Professors/Lab Managers
- Scientists interested in automated flash purification strategies for peptides
What You Will Learn
Attendees will learn about:
- How automated flash chromatography can reduce solvent consumption and improve the efficiency of peptide purification processes
- Practical strategies for integrating greener practices into purification workflows
- How to optimize flash methods to achieve high-purity peptides
Xtalks Partner
Biotage®
Biotage® is a Global Impact Tech Company committed to solving society’s problems. We offer workflow solutions and products to customers in drug discovery and development and diagnostics, analytical testing and water and environmental testing.
Biotage® is contributing to sustainable science with the goal to make the world healthier, greener and cleaner – HumanKind Unlimited.
Our customers span a broad range of market segments, including pharmaceutical, biotech, diagnostic, contract research and contract manufacturers as well as clinical, forensic and academic laboratories, in addition to organizations focused on food safety, clean water and environmental sustainability.
We offer workflow solutions and products to customers in peptide synthesis, drug discovery and development, and analytical testing. Our range of tools increases speed and efficiency of all steps in the peptide synthesis workflow while improving the quality of peptides synthesized.
Biotage® is a leading separations company, providing smart and sustainable workflow solutions for customers in drug discovery, diagnostics, and analytical testing. Our clients range from pharmaceutical and biotech companies to academic labs and organizations dedicated to food safety, clean water, and environmental sustainability. Their flash chromatography solutions allow for rapid, scalable purification of small to large molecules in an effort to reduce lead times and cost at the R&D and production scale.
Biotage® is committed to advancing science with efficiency and care — shaping a better world, one solution at a time.
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