T3P or propanephosphonic acid anhydride, is an exceptional green reagent for use in condensation reactions and has attracted the attention of almost all innovative pharmaceutical companies worldwide during the past decade. Many applications for T3P use are in amidations and peptide coupling reactions — both LPPS (liquid-phase peptide synthesis) and SPPS (solid-phase peptide synthesis). However, the reagent may readily be used for various other functional group transformation reactions including nitrile formation from carboxamides, alcohol oxidation (Swern-type oxidation), ester formation, Lossen rearrangement, Beckmann rearrangement and heterocycle formation.
Register for this webinar to learn about a versatile peptide coupling & water removal reagent that offers several process advantages.
Dr. Peter Talbiersky, Fine Chemicals Business Development Manager, Curia Global, Inc.
Dr. Peter Talbiersky is a chemist by profession. He earned his PhD in organic chemistry at the University Duisburg-Essen in 2009. He started his career as an R&D Manager for a Fine Chemical company in Austria and had various marketing and sales positions in the fine chemicals industry. In 2018 Peter joined Curia, formerly AMRI, as a Sales Manager and is now handling the Curia Fine Chemical product portfolio as the Global Business Development Manager.
Who Should Attend?
R&D Chemists who are using condensation reagents for peptide synthesis or small molecule synthesis
What You Will Learn
Attendees will learn about:
- A green and versatile condensation reagent
- A safe alternative for commonly used condensation reagents like dicyclohexylcarbodiimide (DCC) with reference examples showing the advantages of T3P vs commonly used coupling agents
Curia is a Contract Development and Manufacturing Organization with over 30 years of experience, an integrated network of 29 global sites and over 3,500 employees partnering with customers to make treatments broadly accessible to patients. Our biologics and small molecule offering spans discovery through commercialization, with integrated regulatory and analytical capabilities. Our scientific and process experts and state-of-the-art facilities deliver best-in-class experience across drug substance and drug product manufacturing. From curiosity to cure, we deliver every step to accelerate and sustain life-changing therapeutics. To learn more visit us at curiaglobal.com.