Many people wonder how to gauge a company’s influence in the healthcare sector. One way is to look at its market capitalization, which is the total value of its shares on the stock market.
A larger market cap can signal stability, global reach and a strong capacity to address real-world challenges. In healthcare, these challenges often revolve around improving patient access, lowering costs and driving medical innovation.
Here are 20 leading publicly traded healthcare companies that are driving change and shaping the future of care in 2025.
UnitedHealth (UNH)
UnitedHealth, known for pioneering value‑based care, achieved 2024 revenues of $400.3 billion —an 8% increase — with 2.1 million new domestic consumers and 600,000 additional value‑based care patients at its Optum division. The company projects 2025 revenues of $450 to $455 billion.
Elevance Health (ELV)
Elevance Health delivers integrated healthcare solutions across medical, pharmacy and behavioral care. In 2024, fourth quarter operating revenue reached $45.0 billion and full‑year revenue hit $175.2 billion, driven by higher premium yields, strategic acquisitions and growth in CarelonRx (its integrated pharmacy services division).
CVS Health (CVS)
A leader in retail pharmacy and integrated healthcare, CVS Health is expanding its HealthHUB network and digital care services. In early 2025, CVS launched key initiatives — including a $750,000 grant with Aetna, a $4 million Healthy Aging initiative and a partnership with Duquesne University to address pharmacist shortages — to drive growth and patient engagement.
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