Targeted delivery enhances the safety and efficacy of small nucleic acid drugs. By conjugating siRNA or antisense oligonucleotides (ASOs) with targeting molecules, such as antibodies or peptides, cellular uptake, stability and bioavailability are improved, while immunogenicity and toxicity are reduced.
In this webinar, the featured speakers will introduce technical solutions and application cases for small RNA drug conjugation, focusing on conjugate product identification, precise delivery and gene silencing, as well as differences across methods, offering new insights to boost research efficiency.
The topics that will be covered in this webinar include:
- Advances in Small Nucleic Acid Drug Delivery
- Ligand-Mediated Extrahepatic Delivery Techniques
- Advantages of DAR 1 Antibody-siRNA Conjugate
- Conjugation Solutions for Accelerating Precise Targeted Delivery
Register for this webinar to learn how conjugation strategies are shaping the future of small nucleic acid drug delivery.
Speaker
Jacob Guo, PhD, Director, Nucleic Acid Platform, R&D Dept., GenScript Biotech Corporation
Dr. Jacob Guo is the Director of the Nucleic Acid R&D Platform at GenScript’s Life Science Group, with over a decade of experience in oligonucleotide synthesis. His research focuses on synthetic long oligonucleotides and bioconjugation of nucleic acid drugs.
Jacob holds a PhD in Chemistry from the University of Georgia. He has published five first-author papers in high-impact journals, along with submitting several patents related to oligonucleotide bioconjugation and diagnostic applications.
Message PresenterWho Should Attend?
This webinar will appeal to professionals at all experience levels who are involved in the development of small nucleic acid drugs, with a particular focus on delivery strategies, AOC/POC platforms and siRNA/ASO conjugates. It is relevant to those working in biotech and biopharma companies, universities, research institutes and medical centers, including:
- Students and Researchers interested in small nucleic acid drugs
- Academic Researchers and Laboratory Directors currently in the field of small nucleic acid drugs, particularly delivery strategies
- Research Scientists, Senior Scientists or Project Leaders from the R&D department engaged in small nucleic acid drug projects, especially delivery strategies
What You Will Learn
Attendees will gain insights into:
- Conjugation methods, applications and clinical progress of small nucleic acid drug conjugates
- The characterization of conjugated products using SDS-PAGE, CE-SDS, SEC, IEX and MS
- How DAR1 conjugation strategies enhance the silencing efficiency and stability of conjugated products
- Versatile conjugation solutions tailored to AOC/POC requirements, delivering high-purity conjugated products with precise silencing efficiency
Xtalks Partner
GenScript
GenScript is the leading contract research organization in the world providing gene, peptide, protein, CRISPR, and antibody. Since its foundation in 2002, GenScript has grown exponentially through partnerships with scientists conducting fundamental life science research, translational biomedical research, and early stage pharmaceutical development. The company is recognized as having built a best-in-class capacity and capability for biological research services, encompassing gene synthesis, peptide synthesis, custom antibody and protein engineering, and in vitro and in vivo pharmacology – all with the goal to Make Research Easy.
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