Reducing Caregiver Burden in Alzheimer’s Disease Clinical Trials to Boost Patient Recruitment

Life Sciences, Clinical Trials, Patient Recruitment & Retention,
  • Wednesday, May 24, 2023

Caregivers play a critical role in clinical research since they are the closest and most constant observer of the individual living with dementia. During a clinical trial the ‘caregiver’ becomes the ‘study partner’ and is essential for the success of clinical research. Study retention and adherence to study protocol is a crucial consideration in Alzheimer’s disease trials. Caregivers play a vital role in the landscape of dementia clinical trials by supporting protocol tasks and ensuring participants attend all required visits.

Join this webinar to learn why it is critical that early program design include strategies to address the caregiver needs, thereby reducing burden and boosting patient recruitment and retention.


Sabine Krofczik-Wilhelm, PPD, part of Thermo Fisher Scientific

Sabine Krofczik-Wilhelm, PhD, Executive Director, Neuroscience, PPD, part of Thermo Fisher Scientific

Sabine Krofczik-Wilhelm is an Executive Director in the Neuroscience Therapeutic Unit of the Clinical Research Group. Sabine is the Neurodegenerative Disorders Pillar Head. As a member of the Therapeutic Unit Senior Leadership Team, Sabine is accountable for the strategic and operational delivery of the Neurodegenerative Disorders business. Sabine has a PhD in neurobiology and has more than 15+ years of experience in Project management and 8+ years in dementia. She was involved in the clinical development of ZEPOSIA® (ozanimod), a prescription medicine used to treat relapsing forms of multiple sclerosis (MS) and she has been focusing on dementia clinical research for over seven years.

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Dr. Bruce Hoffen, PPD, part of Thermo Fisher Scientific

Dr. Bruce Hoffen, MD, Principal Investigator, Orlando Clinic, PPD, part of Thermo Fisher Scientific

Dr. Bruce R. Hoffen, MD, is a neurologist with thirty years’ experience in Florida. He is a full-time Principal Investigator for neurology trials with PPD’s Orlando facility. He is board certified in neurology and neuromuscular medicine. Dr. Hoffen’s primary medical interests are in treatment and management of dementia, migraine, Parkinson’s disease and neuromuscular disorders.

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Eve Kamau PPD, part of Thermo Fisher Scientific

Eve Kamau, MSc, RN, Sr. Director Home Trial Services, PPD, part of Thermo Fisher Scientific

Evelyn Kamau (Eve) leads the Home Trial Services division in the digital and decentralized solutions unit of PPD. She has been a nurse for over 20 years with both UK and international nursing experience. In addition to critical care, neurology & community nursing experience, Eve has a special focus in decentralized clinical trials where she has helped support over 100 clinical trials in the home environment for over seven years.

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Who Should Attend?

  • Industry: Biotech and biopharma companies involved in site and patient recruitment for clinical research
  • Healthcare providers and clinicians: Involved in the management of clinical research patients for neurodegenerative trials
  • Clinical research investigators and site directors: Exploring options to reduce patient burden for clinical trial participation
  • Patient Advocacy groups: Bridging the gap between the community and the clinical research ecosystems to develop caregiver-centric trials

What You Will Learn

Attendees will gain insights into:

  • Burdens facing caregivers as extended members of the study team in Alzheimer’s disease /dementia clinical trials
  • Strategies for reducing caregiver burden to increase patient recruitment and retention in these studies
  • Protocol design tailored to caregiver needs
  • Accessing the patient pathway in an aging population

Xtalks Partner


The PPD clinical research business of Thermo Fisher Scientific Inc., the world leader in serving science, enables customers to accelerate innovation and increase drug development productivity. Utilizing patient-centered strategies and data analytics, PPD’s capabilities cover multiple therapeutic areas and include early development, all phases of clinical development, peri- and post-approval, novel approaches to patient recruitment and investigator sites, and comprehensive laboratory services. Recognized as a global industry leader in accelerating promising medicines from early development through regulatory approval and market access, we serve pharma, biotech, medical device and government organizations with custom-tailored solutions, including full-service partnerships and functional service partnerships. As a strategic partner in clinical development and analytical services, we apply cutting-edge technologies, therapeutic expertise and a firm commitment to quality to help customers deliver life-changing therapies.

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