Unlocking precision medicine: An overview of Illumina’s TSO500

ICON’s experience with the TSO500 solid and liquid biopsy assay

As next-generation sequencing (NGS) becomes a ubiquitous part of routine cancer care, its impact in designing and refining drug development remains in flux. Clinical trial design, biomarker identification and cohort analysis have begun to adapt to the changing landscape over the past decade; however, there are challenges with standardization and federation of data.

In this webinar, the speakers will explore the only kitted comprehensive genomic profiling (CGP) assay submitted to the US Food and Drug Administration (FDA) for pre-market approval (PMA) up to this point, TruSight Oncology 500 (TSO500). Available as a research-use-only tool, TSO500 sets the standard for reproducibility across sites, with exceptional accuracy and specificity across a broad range of preserved tissue types.

The expert speakers will also provide an overview of CGP and cover the validation of TSO500 tissue and present preliminary data on circulating tumor DNA (ctDNA). Moreover, the session will explore the application of NGS in oncology clinical trial biomarker studies, demonstrating its pivotal role in advancing personalized medicine in cancer treatment.

Register for this webinar today to gain insights on using NGS in biomarker studies and the impact of comprehensive genomic profiling on advancing personalized cancer treatment.

Speakers

Jin Li, Senior Director, Scientific Affairs, ICON

Jin Li has been in the molecular diagnostics and oncology biomarker field for over 20 years. His current role at ICON includes leading ICON’s NGS specialty lab on assay development and clinical trial assay testing. Prior to working at ICON, he spent seven years at MolecularMD building and leading NGS testing in oncology biomarker testing in clinical trials (MolecularMD was acquired by ICON in 2019).

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Before MolecularMD, he spent two years at Genzyme Genetics, developing high-complexity genetic tests. Jin’s academic credentials include an MD from Tianjin Medical University and a PhD in Molecular and Cellular Physiology from Tufts University.

After completing his doctorate, he served as a postdoctoral researcher and instructor at the Dana-Farber Cancer Institute at Harvard Medical School, where he made critical contributions to the inventions of a novel real-time PCR method and a mutation enrichment method, COLD-PCR.

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Jason Gottwals, Genomic Enablement Manager - AMR, Illumina

Jason Gottwals has been in the molecular diagnostics field for over 22 years. His current role at Illumina is designed to help large cancer sequencing operations recognize and execute opportunities for success. Prior to Illumina, he spent 10 years at PathGroup (PG) designing and executing an oncology program in partnership with Dr. Pranil Chandra, now Chief Genomics Officer at PG.

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