Xtalks Featured Member: James Eldridge, Senior Director, Global Drug Safety, Y-mAbs Therapeutics

We’re proud to introduce Xtalks Featured Community Member James Eldridge, Senior Director of Global Drug Safety at Y-mAbs Therapeutics. Read his insights on drug safety innovation and rare disease oncology leadership below.

What Are Your Proudest Life Science Achievements?

On separate projects, I’ve been able to utilize real-world evidence (RWE) from an internal company safety database in place of external registries or claims/health record data to meet post-marketing requirements from regulators, which saves money, and can resolve requirements sooner. I’m also very proud of my publications utilizing safety data both from real-world and clinical trials. It allows for the proactive dissemination of detailed safety information in rare disease oncology to improve clinical practice and patient care.

What Are Your Day-to-Day Job Highlights?

I perform safety oversight activities for several first-in-human radiopharmaceutical clinical trials utilizing innovative products. I’m coordinating with my clinical and regulatory counterparts to ensure we are meeting the needs of our patients, keeping investigators properly informed and meeting all compliance and regulatory requirements. I also coordinate our DSMBs and chair our internal Safety Committee.

What Are Your Favorite Life Science Innovations?

I’m a big fan of using AI agents to support queries of publicly available regulatory and clinical guidance documents or datasets. It’s definitely changed the way I work. I’ve also been watching advances with ctDNA in oncology for screening, post-treatment monitoring and potentially for predicting treatment outcomes. It’s a developing space that I’m really interested in.

What Is Your Vision for the Future of the Industry?

With advances in automation and AI, I see a future pharmacovigilance landscape where advanced analysis of real-world data (RWD) and clinical insights will allow safety data to be more readily utilized in clinical, medical and regulatory settings. This will allow those of us in safety to play an increasingly more important role in pharma companies over time and have a greater stake in the product life cycle.

Apply Yourself or Nominate a Peer

Do you know someone doing incredible work in the life sciences? Or perhaps you’re proud of your own journey and want to inspire others? We’d love to hear from you.

You can apply to be an Xtalks Featured Community Member or nominate a colleague through our simple online form. It takes just a few minutes, and it could open doors to new conversations, partnerships and recognition across the industry.

Let’s celebrate the people driving life sciences forward — one story at a time.