Theranos’ Elizabeth Holmes Wants New Trial: What Life Science Startups Can Learn from Her Case

Theranos’ Elizabeth Holmes Wants New Trial: What Life Science Startups Can Learn from Her Case

Elizabeth Holmes is set to begin her prison term on April 27.

With just under a week left before Theranos founder Elizabeth Holmes is set to begin her 11-year prison sentence, the former CEO has appealed her conviction, calling it ‘unjust,’ asking for a new trial or a reduced prison term.

Holmes founded healthcare startup Theranos in 2003. The company claimed to have developed a revolutionary blood testing technology that could detect a wide range of diseases with just a few drops of blood. However, it was later alleged that the technology did not work as claimed and the company was engaging in fraudulent activity.

In January 2022, Holmes was found guilty of multiple counts of fraud in a federal trial where it was revealed that she had misled investors, patients and doctors about the capabilities of her company’s blood testing technology. In February, Holmes’ defense requested that she remain out of prison when she first appealed her conviction.

On Monday, Holmes and her attorneys filed a 132-page appeal asking for a reduced sentence. In the filing, they claimed that the federal prosecutor’s case against her “parroted the public narrative” that she knowingly and intentionally misrepresented to investors the capabilities of Theranos technology.

“But the reality differed significantly from that narrative,” Holmes’ attorneys said. “Highly credentialed Theranos scientists told Holmes in real time the technology worked. Outsiders who reviewed the technology said it worked. Theranos’ groundbreaking developments received many patents. And in 2015 the US Food & Drug Administration (FDA) approved an assay on Theranos’ proprietary technology.”

In 2018, the US Securities and Exchange Commission (SEC) charged Holmes and the company’s former president, chief operating officer and Holmes’ ex-boyfriend Ramesh “Sunny” Balwani, with several counts of fraud.

The SEC alleged that Theranos had raised over $700 million from investors through false and misleading statements about the technology’s capabilities and its relationships with major corporations. Holmes and Balwani were also accused of misleading investors about the company’s financial situation and their own personal wealth.

In November 2022, Holmes was sentenced to just over 11 years in prison with three years of state supervision after release. She was found guilty of three counts of wire fraud and one count of conspiracy to commit wire fraud. She was found not guilty on four other counts and jurors were unable to reach a unanimous decision on three other counts. She

An emotional Holmes told the federal court this week that she was “devastated by my failings” and “felt deep pain for what people went through because I failed them.”

In Monday’s court filing, Holmes’ attorneys claimed she believed in her company’s blood test technology and that she was unjustly barred from submitting “compelling evidence” that would have helped her defense.

Related: Johnson & Johnson Offers $8.9 Billion in Talc Lawsuits But Not Enough Says a Plaintiff Group

The attorneys wrote in the filing that the compelling evidence included Balwani’s testimony backing Holmes’ defense that “she did not intend to defraud investors with the financial projections or conspire with Balwani to do so.”

Her attorneys had also argued last week that she should remain free to care for her two young children, including one she welcomed this year with partner Billy Evans. On the other hand, prosecutors said Holmes was a flight risk because she had booked a one-way plane ticket to Mexico during her trial. US District Judge Edward Davila wrote in his ruling last week that this was “ill-advised,” but he added it did not constitute an attempt to flee.

Lessons Life Science Startups Can Learn from the Case of Theranos’ Elizabeth Holmes

The Theranos Elizabeth Holmes case, which has been the subject of several documentaries and podcasts including an HBO documentary called ‘The Inventor’ and a Hulu miniseries, has been seen as a cautionary tale about the dangers of startup culture and the pressure to succeed at all costs.

Theranos was able to raise hundreds of millions of dollars from investors based on false promises and misleading claims.

Holmes’ case provides several important lessons for entrepreneurs and investors embarking on a new biotech, pharma or med tech startup journey. It highlights the importance of ethical standards, due diligence and regulatory compliance, and underscores the potential risks associated with over-hyped or fraudulent startups.

Life science startups face unique challenges given the highly regulated and complex nature of the industry. Here are some lessons that entrepreneurs in this space can learn from past successes and failures:

Prioritize ethics and integrity: The Theranos case highlights the importance of maintaining ethical standards in business. Entrepreneurs should prioritize integrity and transparency, and ensure that their business practices are in line with legal and ethical standards.

Prioritize scientific rigor: The foundation of any life science startup is the scientific research behind its technology or product. Entrepreneurs in this space should prioritize scientific rigor and invest in high-quality R&D to ensure that their technology or product is safe, effective and well-supported by scientific evidence.

Understand the regulatory landscape: Life science startups must navigate a complex regulatory landscape, which can vary by region and product type. Entrepreneurs should work closely with regulatory agencies and seek guidance from experienced professionals to ensure that they are in compliance with all applicable regulations. In the case of Theranos, the company faced regulatory scrutiny over its blood-testing technology, which ultimately led to its downfall.

Build a strong team: The success of a life science startup depends on having a strong team with a diverse set of skills and experiences. Entrepreneurs should prioritize recruiting talented individuals with experience in scientific research, regulatory affairs and business development.

Communicate effectively: Life science startups must be able to effectively communicate their technology or product to a range of stakeholders, including investors, regulators and the general public. Entrepreneurs should develop clear and concise messaging that highlights the value proposition of their technology or product, while also being transparent about its limitations and risks.

Be honest about your product: Entrepreneurs should be honest about their product and its capabilities. In the case of Theranos, the company made fraudulent claims about its technology, which ultimately led to its downfall. Startups should be transparent about what their product can and cannot do and avoid making promises that cannot be kept.

Beware of founder worship: The Theranos case also highlights the dangers of placing too much faith in a charismatic founder. Holmes was touted to be the next Steve Jobs, made Forbes’ Top 30 under 30 list and was said to be the world’s youngest self-made billionaire. She dropped out of Stanford to start Theranos. Her story is reminiscent of many new rising leaders and founders, so it’s easy for the individual and those around them to get caught up in the fanfare and spotlight. Instead, entrepreneurs should prioritize building a strong team and developing a sustainable business model rather than relying on the charisma and vision of a single individual.

Focus on patient outcomes: Ultimately, the success of a life science startup depends on its ability to improve patient outcomes. Entrepreneurs in this space should prioritize patient safety and work closely with healthcare providers to ensure that their technology or product is meeting the needs of patients.

By following these lessons, life science entrepreneurs can increase their chances of success and build sustainable, impactful businesses that benefit patients and society as a whole.