Imaging and therapeutic dosimetry in precision nuclear medicine
Dosimetry is a well-established approach for routine treatment planning in radioligand therapy. The dose of radiation energy absorbed by targeted and surrounding tissue is one of the main parameters that determines the biologic effect of radiation. Therefore, the estimation of absorbed radiation serves as an essential tool for making radiation-based treatments less damaging to the heathy tissue.
The physical and pharmacokinetic interactions of radiopharmaceuticals in the body add complexity to the internal dosimetric process required for radionuclide treatments. Lesion- or organ-based dosimetry approaches can yield parameters that have been extensively studied, such as lesion dose-response correlation, dose-volume histogram and dose heterogeneity map findings. These capabilities allow dosimetric data to offer a more suitable correlation between biologic effect and clinical outcomes.
Register for this webinar today to understand the vital role of dosimetry in enhancing radiation-based treatments and minimizing damage to healthy tissue.
Speakers
Edward Ashton, Sr. Director, Oncology Imaging, Medical Imaging & Cardiac Safety Solutions, ICON
Edward Ashton has supervised more than 300 clinical trials over the past 24 years. He holds a PhD from the University of Rochester with a specialization in medical imaging and was one of the founders of the imaging core lab VirtualScopics. Prior to that, he spent five years working for the federal government.
Carley Hartings, Imaging Scientist 1, Medical Imaging & Cardiac Safety Solutions, ICON
Carley Hartings has 15 years of clinical research experience working on Phase I through Phase IV clinical trials from the site, sponsor and CRO perspectives. She has clinical experience in multiple imaging modalities, including PET, CT, SPECT, MRI and Gamma. Carley has extensive experience in data management processes and has supported numerous clinical trial roles from pharmacovigilance to FDA briefing book preparation.
Who Should Attend?
This webinar will appeal to anyone working on clinical trials involving radiopharmaceuticals:
- CTAs
- Project Managers
- Medical Leads
- Medical monitors
What You Will Learn
During this webinar, attendees will learn about:
- The different lesion- and organ-based dosimetry approaches, including dose-response correlations, dose-volume histograms and dose heterogeneity maps
- How dosimetry helps in estimating absorbed radiation doses, allowing for optimization of radiation treatments to reduce collateral damage to healthy tissue
- How dosimetric data can provide a better correlation between the biologic effects of radiation and clinical outcomes
Xtalks Partner
ICON
ICON is the world’s leading clinical research organisation, powered by healthcare intelligence. From molecule to medicine, we advance clinical research providing a comprehensive suite of outsourced development and commercialisation services to pharmaceutical, biotechnology, medical device and government and public health organisations. We develop new innovations, drive emerging therapies forward and improve patient lives. Our outsourcing models can be adapted to suit small local trials to large global programs, including full service, standalone services, FSP and full asset development.
With headquarters in Dublin, Ireland, ICON employs approximately 41,150 employees in 113 locations in 53 countries.
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