DPYD, From Guidelines to Go-Live: Implementing Testing in the Lab

Biotech, Drug Discovery & Development, Healthcare, Laboratory Technology, Life Science, Pharma,
  • Wednesday, March 25, 2026

Certain DPYD variants are associated with an increased risk of severe toxicity from fluoropyrimidine therapy, making pre-treatment DPYD testing an important component of pharmacogenomics (PGx)- guided care. However, laboratories and health systems may face challenges when translating clinical recommendations into routine testing workflows.

This webinar explores how organizations can move from guideline awareness to practical implementation of DPYD testing.

The featured speakers will review the clinical relevance of DPYD testing, consensus recommendations for DPYD variants and current testing methodologies used in pharmacogenomics programs. They will also summarize key findings from the literature on DPYD implementation and the factors influencing adoption in clinical settings.

The webinar will further examine operational considerations that affect implementation, including provider education, EHR integration, reimbursement and result reporting. Examples of pharmacogenomic reporting approaches and discrete result data will be discussed to illustrate how workflow-aligned integration can support consistent ordering, interpretation and clinical follow-through.

Register for this webinar to learn how DPYD testing can move from guidelines to go-live through practical PGx reporting strategies and clinical workflow integration.

Speakers

Emily Morris, MSc CCGC, Account Executive, GenXys

Emily Morris, MSc CCGC, Account Executive, GenXys

Emily Morris is an Account Executive at GenXys and a board-certified Genetic Counselor. In her role at GenXys, she partners with laboratories and health systems to support successful pharmacogenomics and precision prescribing programs, with a focus on practical workflows, actionable reporting and integrated clinical decision support.

 

Message Presenter
Dr. Vicky Pratt, Director of Scientific Affairs, PGx, Agena Bioscience

Dr. Vicky Pratt, Director of Scientific Affairs, PGx, Agena Bioscience

Dr. Pratt is the Past President of the Association for Molecular Pathology. Dr. Pratt continues to serve on the Centers for Disease Control and Prevention (CDC) GeT-RM program for reference materials for Molecular Genetics, the National Academy of Medicine’s Roundtable on Genomics and Precision Health and the American Medical Association’s (AMA) Molecular Pathology Current Procedural Terminology (CPT) Advisory committee.

Dr. Pratt graduated with a PhD in Medical and Molecular Genetics from Indiana University School of Medicine. Her fellowship training was in PhD Medical and Clinical Molecular Genetics at Henry Ford Hospital, Detroit, MI.

 

Message Presenter

Who Should Attend?

This webinar is for audiences working in reference laboratories offering pharmacogenetic (PGx) testing, commercial companies offering PGx services or academic medical centers and hospitals offering PGx testing.

Relevant job titles include:

  • Physician
  • Pharmacist
  • Laboratory Technician, Manager and Director
  • Pathologist
  • Medical Laboratory Scientist
  • Medical Director and more

What You Will Learn

Attendees will gain insight into:

  • Consensus recommendations for DPYDPGx testing
  • Overcoming operational barriers and other factors influencing adoption
  • Addressing common challenges often faced by laboratories and health systems
  • Understanding how PGx reports and EHR integration can facilitate adoption

Xtalks Partners

Agena Bioscience

Agena Bioscience is dedicated to enabling targeted genomic discoveries that fit the realities of modern laboratories. For more than 25 years, we have partnered with molecular laboratories to help answer defined genetic questions quickly and efficiently – all with a single, flexible platform.

 

GenXys

GenXys is a configurable precision prescribing and intelligence platform that embeds actionable clinical insight into existing healthcare workflows. GenXys enables laboratories – from independent labs to large institutional environments – to operationalize complex clinical and genomic data at scale. Acting as the connective tissue across the prescribing journey, the platform orchestrates intelligence between laboratories, providers, payers, pharmacy benefit managers, and patients, ensuring the right information reaches the right stakeholder at the right time to support safer prescribing and efficient access to therapy.

 

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