Exploring Applications of CAR-T Therapy Outside Oncology: Strategies for Applying Lessons Learned

Life Sciences, Clinical Trials, Drug Discovery & Development, Cell and Gene Therapy,
  • Wednesday, June 19, 2024 | 11am EDT (NA) / 4pm BST (UK) / 5pm CEST (EU-Central)
  • 60 min

Video coming soon

Discover an insightful webinar delving into the expanding horizons of CAR-T therapy beyond oncology.

CAR-T therapy stands at the forefront of medical innovation offering novel treatments for cancer and promising avenues for addressing a wide array of non-oncological diseases. Explore how these therapies are poised to revolutionize treatment paradigms and the adaptation of CAR-T therapy to immunomodulatory approaches for autoimmune diseases, infectious diseases, neurodegenerative disorders, cardiovascular diseases and other non-oncologic conditions.

This webinar focuses on the seamless transition of oncology expertise into non-oncological realms, illustrating how clinical development and operational insights gleaned from managing cancer treatments can be effectively applied to enhance patient care in other disease contexts. Drawing parallels between the complexities of oncology clinical development and the challenges inherent in other therapeutic areas, the expert speakers will elucidate the invaluable lessons learned and strategies devised within the field of oncology that can be leveraged to optimize outcomes in diverse medical domains.


The expert speakers will examine the evolutionary trajectory of biologic therapies, noting how less complex treatments such as monoclonal antibodies have successfully expanded beyond oncology into rheumatology, autoimmune diseases and beyond. This journey serves as a testament to the adaptability and versatility of advanced therapeutic modalities, hinting at a future where cell and gene therapies seamlessly integrate into the fabric of modern medicine, offering hope and healing to patients worldwide.

They will also explore the current and future landscape of CAR-T therapy, highlighting its diverse applications and potential. From revolutionizing treatment approaches in non-oncological diseases to leveraging operational oncology experience for broader therapeutic insights, this webinar will provide valuable lessons and insights into the transformative power of CAR-T therapy across various therapeutics.

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Register for this webinar today to gain insights into the adaptation of CAR T-cell therapy to various non-oncologic conditions.


Frederick Derosier, Fortrea

Frederick Derosier, DO, Vice President, Rare Disease, Advanced Therapies, and Pediatrics, Fortrea

Dr. Frederick Derosier has 10 years of clinical practice and more than 22 years of clinical development experience in the pharmaceutical industry, focused in neurosciences and rare diseases, across large/mid-sized pharma and biotechs. Dr. Derosier’s experience broadly extends from translational/early phase development through product launch to late phase/post-marketing studies and lifecycle management and encompasses a wide array of therapeutic platforms. He joined Fortrea in 2017 and provides medical/scientific leadership for clinical development programs involving rare diseases and/or advanced therapeutics.

Message Presenter
Dr. Brian Hamilton, Fortrea

Dr. Brian Hamilton, MD, PhD, Senior Medical Director, Fortrea

Dr. Brian Hamilton is Senior Medical Director for Fortrea, based in Newton, Massachusetts. He serves as Fortrea’s Subject Matter Expert for cellular immune-oncology as well as CAR-T and gene therapy. He also serves as global lead project Physician on clients’ drug development projects.

Dr. Hamilton has more than 35 years of experience in pediatric medicine, immunology, hematopoietic stem cell transplantation and clinical research and development. Before joining Fortrea, he served as Executive Medical Monitor for Chiltern International.

He has also held senior-level medical director, director physician, regulatory affairs and clinical research positions with Galena Biopharma, AstraZeneca, Onyx Pharmaceuticals, Wyeth Oncology, and other pharmaceutical and biotech firms. Dr. Hamilton joined our company in August 2018.

Message Presenter
Jan Skoumal,Fortrea

Jan Skoumal, Executive Director, Global Project Delivery, Oncology, Fortrea

Jan Skoumal joined Fortrea in mid-2022 and has over 25 years of drug development experience specializing in immuno-oncology in pharma/biotech and CRO environments. He currently is in the operational executive leadership team for Cell and Gene Therapy in Oncology at Fortrea.

Jan is a pragmatic, innovative clinical development leader with over 10 years of experience in cell and gene therapy development, building and managing early-phase immuno-oncology portfolios and operationalising various protocols and programs (autologous/allogenic, hematologic/solid tumors, CAR-T/TCR/TIL, T-Cell engagers, and other cell constructs) that have resulted in four BLA submissions in the immuno-oncology space.

Message Presenter

Who Should Attend?

This webinar will be useful for bio/pharmaceutical and biotechnology professionals working in the following areas:

  • Autoimmune and Inflammatory diseases, Oncology, Immuno-oncology: Sponsors with a pipeline supporting advanced therapies
  • CAR-T cell therapy: industry contributors with an interest in cell, gene, and advanced therapies
  • Trial optimization: anyone working on trial design and optimization for the latest models including patient-centric design
  • Investigator site relations: Investigators and all stakeholders responsible for identifying and working with sites
  • Patient recruitment: all clinical trial staff that focus on recruitment and relationships with patient advocacy groups

What You Will Learn

Attendees will learn about:

  • Current advancements and future prospects in cell and gene therapy
  • Understand the latest developments shaping the field
  • Nature of CAR-T therapy and how the transition from oncology to non-oncology indications presents challenges and complexities running clinical trials
  • How lessons learned from oncology can be translated into other therapeutic areas for enhancing patient outcomes

Xtalks Partner


Fortrea is a leading global provider of clinical development and patient access solutions to the life sciences industry. We partner with emerging and large biopharmaceutical, medical device and diagnostic companies to drive healthcare innovation that accelerates life changing therapies to patients in need. Fortrea provides phase I-IV clinical trial management, clinical pharmacology, differentiated technology enabled trial solutions and post-approval services. Fortrea’s solutions leverage three decades of experience spanning more than 20 therapeutic areas. Our talented and diverse team of more than 19,000 people working in more than 90 countries is scaled to deliver focused and agile solutions to customers globally.

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