Neuromuscular disorders affect the neuromuscular system and affect the nerves that control the muscles, the muscles themselves, and the interface between the nerves and the muscles. These disorders include amyotrophic lateral sclerosis (ALS), muscular dystrophy, myositis, spinal muscular atrophy, amongst others. Many of these diseases are genetic, such as Duchenne muscular dystrophy, while others, such as sporadic inclusion body myositis (sIBM) are idiopathic autoimmune inflammatory myopathies.
There are currently no cures for any of these diseases. Regardless of the etiology of the muscle disease, the measurable changes that can be seen through imaging have a great deal of commonality – there is often inflammation, fatty infiltration, muscle atrophy, and fibrosis. Many of these characteristics can be quantified through imaging, and this webinar will discuss how to apply different imaging techniques to make these measurements in the context of a clinical trial.
Register for this webinar to learn about the importance of choosing the right imaging modality for clinical trials of neuromuscular disorders.
Jonathan Riek, PhD, VP, Musculoskeletal & Metabolic Imaging, Philips BioTel Research
Jonathan Riek, PhD, has served as the Vice President of Musculoskeletal & Metabolic Imaging for Philips BioTel Research since 2001 and is responsible for all musculoskeletal and metabolic disease imaging studies, including arthritis, neuromuscular disorders, diabetes, and liver diseases, such as NASH and NAFLD. He holds four patents and has published many articles on various topics regarding MRI.
He has a PhD in Electrical Engineering from the University of Rochester, and his doctoral thesis was on motion and artifact reduction in MRI. He worked on the development of a 3D CT scanner as a postdoctoral researcher, then spent 7 years in the research labs at the Eastman Kodak Company. While at Kodak, Jonathan worked in the areas of motion estimation, frame rate conversion, and video compression.
Who Should Attend?
This webinar will benefit medical and non-medical professionals in the biopharmaceutical industry, especially those supporting neuromuscular disease drug development with roles in:
- Clinical Research
- Clinical Development
- Imaging Science
- Medical Affairs
- Clinical Operations
- Project Management
- Regulatory Affairs
What You Will Learn
Join this webinar to learn about:
- The challenges and opportunities in conducting neuromuscular clinical trials
- The changes to muscle tissue that are common to most neuromuscular disorders
- Different imaging modalities, and how to choose the right one for a given trial
Philips BioTel Research
Philips BioTel Research is an industry leader in medical imaging and cardiovascular safety testing for clinical trials. Philips BioTel Research offers global operational support for cardiovascular monitoring in all therapeutic areas, and advanced imaging services in oncology, cardiovascular, metabolic, musculoskeletal, neurologic, and medical device studies. Their experienced research team comprises key opinion leaders, board-certified cardiologists and radiologists, sub-specialty scientists, and highly trained technicians — who acquire, evaluate, and report high-quality data through an efficient, cloud-based infrastructure. Many biopharmaceutical trial sponsors rely on our scientific leaders to help design and optimize their protocols and statistical analysis plans. We have conducted clinical trials contributing to the market approval of nearly 100 new drugs to date.