Improve Data Quality With Multicolor Super‑Resolution Imaging
Earn a Certificate of Live Attendance
AI Webinar Explorer available after event
About this webinar
Super-resolution imaging can reveal biological detail that conventional confocal microscopy cannot resolve, but many workflows still force researchers to choose between resolution, speed, multicolor capability and quantitative confidence. Sequential acquisition can introduce temporal mismatches between channels, while detector saturation, noise and repeated setting adjustments can slow experiments and compromise valuable data.
This webinar explores how advances in image scanning microscopy support faster, simultaneous multicolor super-resolution imaging while maintaining quantitative accuracy. The session will examine how silicon photomultiplier technology combines sensitive detection, broad dynamic range and photon-resolving capability within a simultaneous multicolor super-resolution workflow.
The featured speakers will demonstrate how researchers can capture up to four super-resolution channels in one scan without switching between channels. By recording multiple biological events simultaneously, this approach helps preserve temporal relationships and ensure that colocalization data reflects the biology rather than instrument timing or channel-registration differences.
The session will also examine how advanced detector technology enables super-resolution imaging with a wide linear dynamic range and absolute photon quantitation comparable to those available in confocal acquisition. Faint subcellular signals and bright labels can be captured together without clipping, repeated gain adjustments or reacquisition. The featured speakers will discuss imaging approaches that achieve resolution down to 80 nm in XY and 200 nm in Z, while live-mode super-resolution imaging can maintain resolution down to 120 nm in XY and 350 nm in Z.
Application examples will illustrate how near-zero-noise cooled detection preserves signal-to-noise during high-speed scanning, supporting fast multicolor imaging of dynamic processes and larger samples. The session will address reproducibility through absolute photon counts, laser-power monitoring and system-performance checks, as well as how modular detector technology supports both super-resolution and standard confocal imaging workflows.
Register for this webinar to learn how super-resolution imaging improves multicolor acquisition and quantitative data reliability.
Who should attend
- Cell and Molecular Biologists
- Neuroscience and Developmental Biology Researchers
- Cancer, Organoid and Drug Discovery Researchers
- Live-cell, colocalization and quantitative imaging users
- Microscopy Core Facility Managers and Imaging Specialists
- Principal Investigators, Laboratory Managers and Technical decisionmakers
- Researchers planning a new confocal system, adding super-resolution or upgrading an existing platform
What you will learn
- Discover how simultaneous acquisition of up to four super-resolution channels in one scan preserves temporal relationships and reduces sequential-channel mismatch
- See how silicon photomultiplier technology combines wide linear dynamic range, low noise and photon-resolving capabilities to capture faint and bright signals
- Learn how advanced imaging technologies achieve resolution down to 80 nm in XY and 200 nm in Z, and 120 nm in XY and 350 nm in Z during live-mode imaging
- Explore how photon quantitation, laser-power monitoring and modular detector technology support reproducible confocal and super-resolution imaging
Featured Speakers
Bülent Peker, PhD
Bülent Peker, PhD, is a Global Product Marketing Manager at Evident Scientific, focusing on laser scanning microscopy. He received his PhD in Physical Chemistry, working on time-resolved two-photon microscopy. He has been with Olympus and Evident Scientific since 2007, contributing to the introduction of new laser scanning microscopes. He is responsible for global marketing, product messaging and launch planning for the high-end microscopy portfolio.
George Glekas, PhD
George Glekas, PhD, is a National Applications Specialist at Evident Scientific, focusing on laser scanning systems. He received his PhD in Biochemistry from the University of Illinois, studying chemotaxis. Further postdoctoral work at the University of North Carolina was heavily focused on developing novel biosensors. He has been with Evident Scientific since 2016 and is responsible for training, applications support and new product development.
Partner for this event
EVIDENT SCIENTIFIC
Evident creates optical technology that help researchers to illuminate the unseen. Building on more than a century of optical expertise, Evident combines advanced optics, detection technology, intelligent software and application-focused support for life science research. The FLUOVIEW™ FV5000 is a modular imaging platform designed to grow with changing scientific needs—from confocal imaging to simultaneous multicolor super resolution and multiphoton applications. Its new SilVIR-RAY detector uses SilVIR™ silicon photomultiplier technology to combine wide linear dynamic range, near-zero noise and absolute photon quantitation with fast image scanning microscopy. Researchers can capture up to four super-resolution channels simultaneously, supporting high-quality, reproducible imaging without compromising signal, speed or measurement.