An Automated Peptide Synthesis and Purification Platform to Overcome Operational Complexity

Life Sciences, Laboratory Technology,
  • Thursday, October 05, 2023 | 3pm EDT / 2pm CDT / 12pm PDT / 9pm CEST (EU-Central)
  • 60 min

Traditional peptide synthesis workflows rely on separate synthesis and purification machines, which pose challenges in terms of speed and throughput, as well as the complexity of the hardware setup and operation from start to finish. However, to facilitate the development of novel peptide drugs, peptide developers need simple, integrated and parallel solutions without sacrificing process reliability and robustness.

The PurePep® Chorus synthesizer addresses this need by implementing automated synthesis and purification of up to six peptides in a single instrument. Induction heating capabilities help complete the synthesis of even the most difficult peptides in a very short time. The chemoselective purification method using catch-and-release linker technology recovers peptides with minimal hands-on time, also from difficult crude profiles.

In this webinar, attendees will learn how the automated and rapid peptide production workflow works with the PurePep Chorus and how it can significantly increase reliability and productivity as demonstrated with the production of a series of difficult neoantigen peptides.

Don’t miss this opportunity to hear first-hand how cutting-edge peptide synthesis and purification technology can revolutionize the peptide processes from start to finish.

Join the featured speakers to learn about a breakthrough solution for rapid and reliable peptide production that integrates synthesis and purification in a single instrument for the first time.

Speaker

Dr. Chloe Mitchell, Protein Technologies AB

Dr. Chloe Mitchell, Field Application Scientist, Gyros Protein Technologies AB

Dr. Chloe Mitchell completed her PhD at the University of Toronto in 2022 under the supervision of Dr. Charles Deber. She worked on designing transmembrane peptides that were targeted toward the protein-protein interface of multidrug resistance efflux pumps in a broad spectrum of multidrug-resistant bacteria. She studied the effect these peptides had on the efflux pump efficiency and lipid bilayer. She joined GPT after graduation as a field application scientist and is now helping the peptide community to reach maximum efficiency with PurePep solutions.

Message Presenter

Who Should Attend?

This webinar will appeal to professionals in the following fields:

  • Drug developers
  • Custom peptide manufacturer
  • Peptide scientists
  • Peptide lab site and project managers

What You Will Learn

Attendees will gain insights into:

  • How to reduce complexity in the lab by performing peptide synthesis and purification in a single instrument
  • The induction heating for fast synthesis of even the most complex peptides
  • The benefits of catch-and-release purification to improve operational reliability
  • How productivity for parallel peptide manufacturing can be improved significantly

Xtalks Partner

Gyros Protein Technologies

Gyros Protein Technologies enables peptide and bioanalytical solutions that help scientists increase biomolecule performance and productivity in research, drug discovery, pre-clinical and clinical development, and bioprocess applications. Our low to mid-scale peptide synthesizer platforms are the PurePep(r) Chorus, Symphony(r) X, and PurePep(r)Sonata(r)+. The PurePep(r) EasyClean (PEC) technology complements the PurePep(r) portfolio with Kits and Services for peptide purification and modification.

These solutions and our chemistries deliver uncompromising purity, flexibility, and quality for discovery and pre-clinical studies of simple to complex multifunctional peptides up- and downstream. Proprietary high performance nanoliter-scale immunoassay platforms, Gyrolab(r) xPand, Gyrolab(r) xP workstation and Gyrolab xPlore(tm), are used by scientists in leading pharmaceutical, biotech, CRO, and CMO companies for bioanalytical applications such as pharmacokinetics/pharmacodynamics, immunogenicity, and quantitating bioprocess-related impurities. Our peptide and bioanalytical solutions accelerate your discovery, development, and manufacturing of safer biotherapeutics. Gyros Protein Technologies is part of the Biopharmaceutical Division of Mesa Laboratories, Inc.

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